Matches in SemOpenAlex for { <https://semopenalex.org/work/W3032160606> ?p ?o ?g. }
- W3032160606 endingPage "406" @default.
- W3032160606 startingPage "397" @default.
- W3032160606 abstract "Background and Objective: Immune thrombocytopenia (ITP) is a common bleeding disorder in childhood. The management of ITP in children is controversial, requiring personalized assessment of patients and therapeutic choices. Thrombopoietin receptor agonists (TPO-RAs), eltrombopag and romiplostim, have been shown to be safe and effective for the treatment of pediatric ITP. The aim of our research is to define the role of thrombopoietin receptor agonists in the management of pediatric ITP. Methods: This review focuses on the use of TPO-RAs in pediatric ITP, in randomized trials and in clinical routine, highlighting their key role in the management of the disease. Results: Eltrombopag and romiplostim appear effective treatment options for children with ITP. Several clinical studies have assessed that the use of TPO-RAs increases platelet count, decreases bleeding symptoms and improves health-related quality of life. Moreover, TPO-RAs are well tolerated with minor side effects. Conclusion: Although long term efficacy and safety of TPO-RAs still require further investigations, their use is gradually expanding in the clinical practice of children with ITP." @default.
- W3032160606 created "2020-06-05" @default.
- W3032160606 creator A5001024908 @default.
- W3032160606 creator A5004345295 @default.
- W3032160606 creator A5028743501 @default.
- W3032160606 creator A5030655484 @default.
- W3032160606 creator A5047053578 @default.
- W3032160606 creator A5054107558 @default.
- W3032160606 creator A5058063828 @default.
- W3032160606 date "2021-03-01" @default.
- W3032160606 modified "2023-10-18" @default.
- W3032160606 title "Thrombopoietin Receptor Agonists in Children with Immune Thrombocytopenia: A New Therapeutic Era" @default.
- W3032160606 cites W1509820083 @default.
- W3032160606 cites W1522218361 @default.
- W3032160606 cites W1588638434 @default.
- W3032160606 cites W1607509198 @default.
- W3032160606 cites W1874142609 @default.
- W3032160606 cites W1971250997 @default.
- W3032160606 cites W1980002878 @default.
- W3032160606 cites W1981370197 @default.
- W3032160606 cites W1984073642 @default.
- W3032160606 cites W1994063537 @default.
- W3032160606 cites W1996233346 @default.
- W3032160606 cites W1998560266 @default.
- W3032160606 cites W2005434060 @default.
- W3032160606 cites W2011497626 @default.
- W3032160606 cites W2011676619 @default.
- W3032160606 cites W2014207233 @default.
- W3032160606 cites W2014278636 @default.
- W3032160606 cites W2020910729 @default.
- W3032160606 cites W2026047633 @default.
- W3032160606 cites W2031024370 @default.
- W3032160606 cites W2034909356 @default.
- W3032160606 cites W2038554277 @default.
- W3032160606 cites W2049217001 @default.
- W3032160606 cites W2051662883 @default.
- W3032160606 cites W2066536897 @default.
- W3032160606 cites W2070214673 @default.
- W3032160606 cites W2074183555 @default.
- W3032160606 cites W2076789749 @default.
- W3032160606 cites W2079785691 @default.
- W3032160606 cites W2087784094 @default.
- W3032160606 cites W2094733807 @default.
- W3032160606 cites W2103710704 @default.
- W3032160606 cites W2104190548 @default.
- W3032160606 cites W2122735473 @default.
- W3032160606 cites W2127175732 @default.
- W3032160606 cites W2139745353 @default.
- W3032160606 cites W2144118333 @default.
- W3032160606 cites W2161864936 @default.
- W3032160606 cites W2174092443 @default.
- W3032160606 cites W2204521850 @default.
- W3032160606 cites W2295126790 @default.
- W3032160606 cites W2297402754 @default.
- W3032160606 cites W2324570401 @default.
- W3032160606 cites W2328012130 @default.
- W3032160606 cites W2342342288 @default.
- W3032160606 cites W2342531607 @default.
- W3032160606 cites W2394658598 @default.
- W3032160606 cites W2529699358 @default.
- W3032160606 cites W2579949531 @default.
- W3032160606 cites W2580485709 @default.
- W3032160606 cites W2586334726 @default.
- W3032160606 cites W2592969379 @default.
- W3032160606 cites W2604329986 @default.
- W3032160606 cites W2613164134 @default.
- W3032160606 cites W2617335035 @default.
- W3032160606 cites W2629461645 @default.
- W3032160606 cites W2747634106 @default.
- W3032160606 cites W2749427025 @default.
- W3032160606 cites W2777354420 @default.
- W3032160606 cites W2787953308 @default.
- W3032160606 cites W2799302422 @default.
- W3032160606 cites W2895566901 @default.
- W3032160606 cites W2897173469 @default.
- W3032160606 cites W2906950405 @default.
- W3032160606 cites W2916393866 @default.
- W3032160606 cites W2921220965 @default.
- W3032160606 cites W2934060647 @default.
- W3032160606 cites W2944075675 @default.
- W3032160606 cites W2954221431 @default.
- W3032160606 cites W2982068879 @default.
- W3032160606 cites W3008268408 @default.
- W3032160606 cites W4211106014 @default.
- W3032160606 cites W2899344264 @default.
- W3032160606 doi "https://doi.org/10.2174/1871530320666200531142244" @default.
- W3032160606 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32473624" @default.
- W3032160606 hasPublicationYear "2021" @default.
- W3032160606 type Work @default.
- W3032160606 sameAs 3032160606 @default.
- W3032160606 citedByCount "2" @default.
- W3032160606 countsByYear W30321606062022 @default.
- W3032160606 countsByYear W30321606062023 @default.
- W3032160606 crossrefType "journal-article" @default.
- W3032160606 hasAuthorship W3032160606A5001024908 @default.
- W3032160606 hasAuthorship W3032160606A5004345295 @default.
- W3032160606 hasAuthorship W3032160606A5028743501 @default.
- W3032160606 hasAuthorship W3032160606A5030655484 @default.