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- W3032165666 abstract "ObjectiveTo analyze the clinical characteristics and prognosis of patients with hepatic veno-occlusive disease (HVOD) induced by Sedum aizoon.MethodsThe clinical data of 28 cases of HVOD induced by Sedum aizoon in our hospital was retrospectively analyzed, and the clinical characteristics were analyzed. According to the prognosis results, the patients were divided into the good prognosis group and the poor prognosis group, and the related laboratory indexes test results were compared between the two groups.ResultsThe clinical manifestations of 28 cases of HVOD induced by Sedum aizoon were mainly ascites (96.43%), abdominal distension (85.71%), and jaundice (42.86%). The results of laboratory test showed that the abnormal liver function and coagulation function were shown in part of patients, and mainly were abnormal total bilirubin (TBIL) (85.71%), alkaline phosphatase (ALP) (82.14%), alanine aminotransferase (ALT) (75.00%). The levels of prothrombin time (PT), ALT, and aspartate aminotransferase (AST) in the poor prognosis group were significantly higher than those in the good prognosis group [(19.64±1.57)s vs.(16.17±2.25)s, (479.61±252.69)U/L vs.(249.65±141.58)U/L, (421.52±241.58)U/L vs.(206.39±102.47)U/L] (P<0.05).ConclusionsHVOD induced by Sedum aizoon has ascites, abdominal distension, and jaundice as the main clinical manifestations. And the more serious the damage degree of liver function and coagulation function are, the worse the prognosis is, therefore the timely diagnosis and treatment are needed to improve the prognosis.Key words: Sedum aizoon; Hepatic veno-occlusive disease; Liver function" @default.
- W3032165666 created "2020-06-05" @default.
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- W3032165666 date "2018-03-01" @default.
- W3032165666 modified "2023-09-23" @default.
- W3032165666 title "Clinical characteristics of 28 cases of hepatic veno-occlusive disease induced by Sedum aizoon" @default.
- W3032165666 doi "https://doi.org/10.3760/cma.j.issn.1007-1245.2018.05.009" @default.
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