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- W3032194906 abstract "High mobility group box-1 protein (HMGB1) is widely involved in various inflammatory response processes in the body.The receptor for advanced glycation end-products (RAGE) and some Toll-like receptors are its main receptors.A large number of studies have confirmed that HMGB1 can induce various physiological and pathological effects of inflammatory response, immune response, tumor occurrence through the RAGE receptor pathway, and participate in the occurrence and development of various diseases.HMGB1 is widely expressed in lung tissues, and HMGB1/RAGE signal has been shown to be involved in the pathogenesis of many chronic airway diseases.Especially in the occurrence and development of asthma, HMGB1/RAGE signal has been confirmed to play an important role in it, but the specific mechanism is still unclear.This article preliminarily explains the role of HMGB1/RAGE in respiratory diseases, especially asthma, and related research progress.Key words: HMGB1/RAGE signal; Respiratory diseases; Asthma" @default.
- W3032194906 created "2020-06-05" @default.
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- W3032194906 date "2020-02-05" @default.
- W3032194906 modified "2023-09-24" @default.
- W3032194906 title "HMGB1/RAGE signal and respiratory diseases and its research progress" @default.
- W3032194906 doi "https://doi.org/10.3760/cma.j.issn.1673-436x.2020.03.014" @default.
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