Matches in SemOpenAlex for { <https://semopenalex.org/work/W3032197417> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W3032197417 endingPage "159" @default.
- W3032197417 startingPage "157" @default.
- W3032197417 abstract "Objective Increased serum uric acid level is associated with type 2 diabetes (T2DM) through the mechanism of oxidative stress.As the rate-limiting enzyme in the degradation of purines in humans,xanthine oxidoreductase (XOR)catalyzes the final two reactions of purine catabolism,oxidizing hypoxanthine to xanthine,and xanthine to uric acid.The aim of this study is to investigate the association between serum XOR activity and T2DM.Methods A total of 270 patients with T2DM and 140 age-and-gender-matched health controls were enrolled in the study.The clinical examinations such as weight and height were conducted in the morning after an overnight fast.Serum XOR activity and other biochemical parameters like triglyceride,total cholesterol,high density lipoprotein cholesterol,fasting plasma glucose and uric acid levels were measured.Results Serum XOR activity was significantly elevated in T2DM patients compared with that in the controls (31.2 ± 8.91 vs 4.6 ± 0.91 U/L,P ＜0.01).Serum XOR activity was significantly elevated in T2DM patients complicated with lower extremity arterial disease compared to that in patients without lower extremity arterial disease (42.1 ± 8.43 vs 23.7 ± 5.31 U/L,P ＜ 0.01).Conclusion High XOR activity plays an important role in onset and development of T2DM.Key words: Type 2 diabetes; Atherosclerosis; Xanthine oxidoreductase" @default.
- W3032197417 created "2020-06-05" @default.
- W3032197417 creator A5020968816 @default.
- W3032197417 date "2013-04-25" @default.
- W3032197417 modified "2023-09-23" @default.
- W3032197417 title "The significance of serum xanthine oxidoreductase in patients with type 2 diabetes" @default.
- W3032197417 doi "https://doi.org/10.3760/cma.j.issn.1674-6090.2013.02.021" @default.
- W3032197417 hasPublicationYear "2013" @default.
- W3032197417 type Work @default.
- W3032197417 sameAs 3032197417 @default.
- W3032197417 citedByCount "0" @default.
- W3032197417 crossrefType "journal-article" @default.
- W3032197417 hasAuthorship W3032197417A5020968816 @default.
- W3032197417 hasConcept C126322002 @default.
- W3032197417 hasConcept C134018914 @default.
- W3032197417 hasConcept C151400659 @default.
- W3032197417 hasConcept C169586020 @default.
- W3032197417 hasConcept C181199279 @default.
- W3032197417 hasConcept C185592680 @default.
- W3032197417 hasConcept C2776476023 @default.
- W3032197417 hasConcept C2777180221 @default.
- W3032197417 hasConcept C2778102346 @default.
- W3032197417 hasConcept C2778163477 @default.
- W3032197417 hasConcept C2778913445 @default.
- W3032197417 hasConcept C2779470414 @default.
- W3032197417 hasConcept C2779881121 @default.
- W3032197417 hasConcept C2781116151 @default.
- W3032197417 hasConcept C2910068830 @default.
- W3032197417 hasConcept C55493867 @default.
- W3032197417 hasConcept C555293320 @default.
- W3032197417 hasConcept C71924100 @default.
- W3032197417 hasConceptScore W3032197417C126322002 @default.
- W3032197417 hasConceptScore W3032197417C134018914 @default.
- W3032197417 hasConceptScore W3032197417C151400659 @default.
- W3032197417 hasConceptScore W3032197417C169586020 @default.
- W3032197417 hasConceptScore W3032197417C181199279 @default.
- W3032197417 hasConceptScore W3032197417C185592680 @default.
- W3032197417 hasConceptScore W3032197417C2776476023 @default.
- W3032197417 hasConceptScore W3032197417C2777180221 @default.
- W3032197417 hasConceptScore W3032197417C2778102346 @default.
- W3032197417 hasConceptScore W3032197417C2778163477 @default.
- W3032197417 hasConceptScore W3032197417C2778913445 @default.
- W3032197417 hasConceptScore W3032197417C2779470414 @default.
- W3032197417 hasConceptScore W3032197417C2779881121 @default.
- W3032197417 hasConceptScore W3032197417C2781116151 @default.
- W3032197417 hasConceptScore W3032197417C2910068830 @default.
- W3032197417 hasConceptScore W3032197417C55493867 @default.
- W3032197417 hasConceptScore W3032197417C555293320 @default.
- W3032197417 hasConceptScore W3032197417C71924100 @default.
- W3032197417 hasIssue "02" @default.
- W3032197417 hasLocation W30321974171 @default.
- W3032197417 hasOpenAccess W3032197417 @default.
- W3032197417 hasPrimaryLocation W30321974171 @default.
- W3032197417 hasRelatedWork W2001110434 @default.
- W3032197417 hasRelatedWork W2032496710 @default.
- W3032197417 hasRelatedWork W2072779286 @default.
- W3032197417 hasRelatedWork W2105068083 @default.
- W3032197417 hasRelatedWork W2165581150 @default.
- W3032197417 hasRelatedWork W2311471373 @default.
- W3032197417 hasRelatedWork W2379760313 @default.
- W3032197417 hasRelatedWork W2409573689 @default.
- W3032197417 hasRelatedWork W2560496509 @default.
- W3032197417 hasRelatedWork W2738116644 @default.
- W3032197417 hasRelatedWork W2767376806 @default.
- W3032197417 hasRelatedWork W2885142967 @default.
- W3032197417 hasRelatedWork W2886157181 @default.
- W3032197417 hasRelatedWork W2940742457 @default.
- W3032197417 hasRelatedWork W2946328047 @default.
- W3032197417 hasRelatedWork W3000738400 @default.
- W3032197417 hasRelatedWork W3010723811 @default.
- W3032197417 hasRelatedWork W3212953114 @default.
- W3032197417 hasRelatedWork W874784363 @default.
- W3032197417 hasRelatedWork W2171910637 @default.
- W3032197417 hasVolume "7" @default.
- W3032197417 isParatext "false" @default.
- W3032197417 isRetracted "false" @default.
- W3032197417 magId "3032197417" @default.
- W3032197417 workType "article" @default.