FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3032243577> ?p ?o ?g. }

• W3032243577 endingPage "439" @default.
• W3032243577 startingPage "435" @default.
• W3032243577 abstract "ObjectiveTo investigate the parafoveal and perifoveal vessel density and the area of foveal avascular zone (FAZ) by optical coherence tomography angiography (OCTA) in diabetic patients with early diabetic retinopathy.MethodsClinical data of in-patients and out-patients with diabetes in Department of Endocrinology of Beijing Hospital from October 2015 to November 2016 were collected. All of the participants underwent examination with OCTA, and were examined for the condition of fundus according to Early Treatment Diabetic Retinopathy Study (ETDRS) international DR staging criteria. Total of 85 eyes from patients without diabetic retinopathy (NDR group) and 23 eyes with diabetic retinopathy (DR group) were checked in the study. Ninety eight eyes from healthy subjects were set as normal control. Differences of vessel density in macular region and the area of FAZ among the three groups were analyzed by analysis of variance and pairwise comparison was done by using LSD method.ResultsThe difference in mean vessel density between the control and patients with diabetes was statistically significant (51%±4% vs 50%±5%, F=5.828, P=0.017). Vessel densities in fovea beside macula lutea, upper part of macula lutea,upward margin of central fovea, temporal margin of central fovea, nasal margin of central fovea of normal control group were all significantly higher than those in patients with diabetes (F=4.794, 6.677, 6.117, 7.294, 4.656, P<0.05). The size of FAZ of control group was significantly smaller than that in patients with diabetes [(0.29±0.08) vs (0.33±0.09) mm2, F=12.30, P=0.001]. Mean vessel densities of control group, NDR group and DR group were tapering off (51%±4% vs 50%±5% vs 47%±4%, F=10.605, P=0.000), and area of FAZ of the three groups increased instead [(0.29±0.08) vs (0.33±0.07) vs (0.38±0.10) mm2, F=10.892, P=0.000]. Therewas significant difference in vessel density in the macular region between the normal control and DR group [mean deviation (I-J value) 4.422, P=0.000], while no significant differences between the normal control and NDR group was found (I-J value 1.196, P=0.051). Significant difference in FAZ area between the normal control and NDR group, and between normal control and DR group were found with LSD method (I-J value 0.043, 0.091, both P<0.05). Similarly, significant differences in mean vessel densities in macular region and FAZ area were found between the NDR group and DR group (I-J value 3.227, 0.048, both P<0.05).ConclusionOCTA can detect early ischemia changes in macular region such as lower vessel density, greater size of FAZ, thus is helpful for early intervention.Key words: Diabetic retinopathy; Optical coherence tomography angiography; Macula lutea; Foveal avascular zone; Vessel density" @default.
• W3032243577 created "2020-06-05" @default.
• W3032243577 creator A5018718326 @default.
• W3032243577 creator A5028293439 @default.
• W3032243577 creator A5065859286 @default.
• W3032243577 date "2017-07-27" @default.
• W3032243577 modified "2023-09-23" @default.
• W3032243577 title "Changes in the parafoveal and perifoveal vessel density and the area of foveal avascular zone in patients with diabetic retinopathy" @default.
• W3032243577 doi "https://doi.org/10.3760/cma.j.issn.1674-5809.2017.07.007" @default.
• W3032243577 hasPublicationYear "2017" @default.
• W3032243577 type Work @default.
• W3032243577 sameAs 3032243577 @default.
• W3032243577 citedByCount "2" @default.
• W3032243577 countsByYear W30322435772022 @default.
• W3032243577 countsByYear W30322435772023 @default.
• W3032243577 crossrefType "journal-article" @default.
• W3032243577 hasAuthorship W3032243577A5018718326 @default.
• W3032243577 hasAuthorship W3032243577A5028293439 @default.
• W3032243577 hasAuthorship W3032243577A5065859286 @default.
• W3032243577 hasConcept C118487528 @default.
• W3032243577 hasConcept C119767625 @default.
• W3032243577 hasConcept C134018914 @default.
• W3032243577 hasConcept C2776391266 @default.
• W3032243577 hasConcept C2777655287 @default.
• W3032243577 hasConcept C2778313320 @default.
• W3032243577 hasConcept C2779736970 @default.
• W3032243577 hasConcept C2779829184 @default.
• W3032243577 hasConcept C2780827179 @default.
• W3032243577 hasConcept C30181142 @default.
• W3032243577 hasConcept C555293320 @default.
• W3032243577 hasConcept C71924100 @default.
• W3032243577 hasConceptScore W3032243577C118487528 @default.
• W3032243577 hasConceptScore W3032243577C119767625 @default.
• W3032243577 hasConceptScore W3032243577C134018914 @default.
• W3032243577 hasConceptScore W3032243577C2776391266 @default.
• W3032243577 hasConceptScore W3032243577C2777655287 @default.
• W3032243577 hasConceptScore W3032243577C2778313320 @default.
• W3032243577 hasConceptScore W3032243577C2779736970 @default.
• W3032243577 hasConceptScore W3032243577C2779829184 @default.
• W3032243577 hasConceptScore W3032243577C2780827179 @default.
• W3032243577 hasConceptScore W3032243577C30181142 @default.
• W3032243577 hasConceptScore W3032243577C555293320 @default.
• W3032243577 hasConceptScore W3032243577C71924100 @default.
• W3032243577 hasIssue "07" @default.
• W3032243577 hasLocation W30322435771 @default.
• W3032243577 hasOpenAccess W3032243577 @default.
• W3032243577 hasPrimaryLocation W30322435771 @default.
• W3032243577 hasRelatedWork W2412896315 @default.
• W3032243577 hasRelatedWork W2618128425 @default.
• W3032243577 hasRelatedWork W2766419787 @default.
• W3032243577 hasRelatedWork W2768132506 @default.
• W3032243577 hasRelatedWork W2885212832 @default.
• W3032243577 hasRelatedWork W2889953117 @default.
• W3032243577 hasRelatedWork W2890581815 @default.
• W3032243577 hasRelatedWork W2892312565 @default.
• W3032243577 hasRelatedWork W2918232590 @default.
• W3032243577 hasRelatedWork W2954885493 @default.
• W3032243577 hasRelatedWork W2998645912 @default.
• W3032243577 hasRelatedWork W3010628320 @default.
• W3032243577 hasRelatedWork W3018494655 @default.
• W3032243577 hasRelatedWork W3031437442 @default.
• W3032243577 hasRelatedWork W3032261966 @default.
• W3032243577 hasRelatedWork W3094874866 @default.
• W3032243577 hasRelatedWork W3097505880 @default.
• W3032243577 hasRelatedWork W3131804217 @default.
• W3032243577 hasRelatedWork W3170591618 @default.
• W3032243577 hasRelatedWork W1032467128 @default.
• W3032243577 hasVolume "9" @default.
• W3032243577 isParatext "false" @default.
• W3032243577 isRetracted "false" @default.
• W3032243577 magId "3032243577" @default.
• W3032243577 workType "article" @default.