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- W3032251189 abstract "Objective To explore the association of human leucocyte antigen (HLA)-DQB1 allele polymorphism with genetic susceptibility in irritable bowel syndrome (IBS) in patients with.Guangdong Hannationality.Methods The genetic typing of DQB1 was conducted by DNA micmarray in 60 patients and healthy subjects.The distribution difference in allele frequency was compared between the two groups.Results The frequency of DQB 1*02 in IBS patients was significantly greater than that in the control subject.The frequency of DQB1*0603 was significantly lower in patients with IBS than in the controls.The frequency of HLA-DQB1 had no significant dlifference with all types of IBS.Conclusions DQB1*02 or DQB1*0603 may be the susceptihility genes in patients with irritable bowel syndrome and with Guangdong Han nationality.Key words: Human leucocyte antigen-DQB1 gene; Irritable bowel syndrome; Genetic susceptibility" @default.
- W3032251189 created "2020-06-05" @default.
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- W3032251189 date "2013-02-01" @default.
- W3032251189 modified "2023-09-23" @default.
- W3032251189 title "Association of DQB1 allele polymorphism with genetic susceptibility in patients with irritable bowel syndrome" @default.
- W3032251189 doi "https://doi.org/10.3760/cma.j.issn.1007-1245.2013.03.020" @default.
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