Matches in SemOpenAlex for { <https://semopenalex.org/work/W3032251607> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W3032251607 endingPage "983" @default.
- W3032251607 startingPage "980" @default.
- W3032251607 abstract "Objective To analyse clinical characteristics of neurofibromatosis type 2 (NF2) and evaluate clinical predictors of the risk of mortality in patients of NF2.Methods A total of 175 cases of NF2 patients,confirmed with Manchester criteria for clinical diagnosis of NF2,were retrospectively studied for the clinical manifestations and imaging.Average age of this group was 29.5 year-old,including 92 males and 83 females.27 cases were inherited cases and 148 were sporadic cases.During the follow-up from 1-255 months,154 NF2 cases still survive while 21 cases died.The median survival time was 208.4 ± 10.6 months (95％ CI,187.6,229.1).The Kaplan-Meier survival analysis were performed for the survive time,examined with the covariates of age at onset of symptoms,age at diagnosis,sex,inheritance (new mutation or inherited case),presence each type of NF2 lesions (intracranial meningiomas,spinal tumors,peripheral neuropathy and ocular disorders).Results Group of aged at onset of symptoms groups ＞ 19 years was significantly higher survival rate than group of aged ≤ 19 years (P =0.006) ; Patients without spinal tumors had significantly higher survival rate than patients with spinal tumors (P =0.009).Cox proportional hazards regression analysis indicated that presence with spinal tumors was the influencing factors for prognosis of NF2 patients.Conclusions NF2 is a clinically hetereogeneous disease with different phenotypes,presence with spinal tumors was associated with poor survival.Key words: Neurofibromatosis type 2; Clinical characteristics; Prognosis" @default.
- W3032251607 created "2020-06-05" @default.
- W3032251607 creator A5008233208 @default.
- W3032251607 creator A5010779145 @default.
- W3032251607 creator A5067782718 @default.
- W3032251607 date "2013-10-28" @default.
- W3032251607 modified "2023-09-28" @default.
- W3032251607 title "Analysis clinical predictors of the risk of mortality in patients with neurofibromatosis type 2" @default.
- W3032251607 doi "https://doi.org/10.3760/cma.j.issn.1001-2346.2013.10.004" @default.
- W3032251607 hasPublicationYear "2013" @default.
- W3032251607 type Work @default.
- W3032251607 sameAs 3032251607 @default.
- W3032251607 citedByCount "0" @default.
- W3032251607 crossrefType "journal-article" @default.
- W3032251607 hasAuthorship W3032251607A5008233208 @default.
- W3032251607 hasAuthorship W3032251607A5010779145 @default.
- W3032251607 hasAuthorship W3032251607A5067782718 @default.
- W3032251607 hasConcept C10515644 @default.
- W3032251607 hasConcept C126322002 @default.
- W3032251607 hasConcept C141071460 @default.
- W3032251607 hasConcept C142724271 @default.
- W3032251607 hasConcept C179755657 @default.
- W3032251607 hasConcept C2776283816 @default.
- W3032251607 hasConcept C2777767895 @default.
- W3032251607 hasConcept C2778679214 @default.
- W3032251607 hasConcept C2778984943 @default.
- W3032251607 hasConcept C2779134260 @default.
- W3032251607 hasConcept C50382708 @default.
- W3032251607 hasConcept C71924100 @default.
- W3032251607 hasConceptScore W3032251607C10515644 @default.
- W3032251607 hasConceptScore W3032251607C126322002 @default.
- W3032251607 hasConceptScore W3032251607C141071460 @default.
- W3032251607 hasConceptScore W3032251607C142724271 @default.
- W3032251607 hasConceptScore W3032251607C179755657 @default.
- W3032251607 hasConceptScore W3032251607C2776283816 @default.
- W3032251607 hasConceptScore W3032251607C2777767895 @default.
- W3032251607 hasConceptScore W3032251607C2778679214 @default.
- W3032251607 hasConceptScore W3032251607C2778984943 @default.
- W3032251607 hasConceptScore W3032251607C2779134260 @default.
- W3032251607 hasConceptScore W3032251607C50382708 @default.
- W3032251607 hasConceptScore W3032251607C71924100 @default.
- W3032251607 hasIssue "10" @default.
- W3032251607 hasLocation W30322516071 @default.
- W3032251607 hasOpenAccess W3032251607 @default.
- W3032251607 hasPrimaryLocation W30322516071 @default.
- W3032251607 hasRelatedWork W1597741367 @default.
- W3032251607 hasRelatedWork W1795732003 @default.
- W3032251607 hasRelatedWork W2052340962 @default.
- W3032251607 hasRelatedWork W2058122536 @default.
- W3032251607 hasRelatedWork W2084460624 @default.
- W3032251607 hasRelatedWork W2112780127 @default.
- W3032251607 hasRelatedWork W2183462000 @default.
- W3032251607 hasRelatedWork W2292773944 @default.
- W3032251607 hasRelatedWork W2391487468 @default.
- W3032251607 hasRelatedWork W2415015138 @default.
- W3032251607 hasRelatedWork W2415732926 @default.
- W3032251607 hasRelatedWork W2419574239 @default.
- W3032251607 hasRelatedWork W2552932379 @default.
- W3032251607 hasRelatedWork W2567909749 @default.
- W3032251607 hasRelatedWork W2603980606 @default.
- W3032251607 hasRelatedWork W2909681172 @default.
- W3032251607 hasRelatedWork W2985438308 @default.
- W3032251607 hasRelatedWork W3028962838 @default.
- W3032251607 hasRelatedWork W3032592448 @default.
- W3032251607 hasRelatedWork W3047710006 @default.
- W3032251607 hasVolume "29" @default.
- W3032251607 isParatext "false" @default.
- W3032251607 isRetracted "false" @default.
- W3032251607 magId "3032251607" @default.
- W3032251607 workType "article" @default.