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- W3032255323 abstract "Objective To observe the effect of the cumulative percentage of ventricular pacing (CUM％ VP) on heart function of patients with right ventricular apical pacing.Methods A cohort study was conducted among 86 patients with sick sinus syndrome (SSS) or atrioventricular block (AVB)after single-chamber ventricular pacemaker implantation.According to the cut-point 90％ of CUM％ VP,the patients were divided into group A (CUM％ VP ≥90％,n =32) and group B (CUM％ VP ＜ 90％,n =54).The primary composite endpoint was defined as new-onset heart failure (NYHA class ≥ Ⅲ or hospitalization for heart failure) and death from all causes.The left ventricular ejection fraction(LVEF),left ventricular end-diastolic diameter(LVEDD) and the QRS duration were measured.Their absolute alterations(△LVEF,△LVEDD,△QRSd) as compared with the baseline measurements were also calculated.Results Before pacemaker implantation,there were no differences in age,sex,basic diseases,cardiac function,and constituent ratio in type of pacemakers between group A and B.There were no death,dropout,and loss to follow-up.By comparing the outcomes of group A with those of group B at the end of the study,it showed that:the absolute decrease in LVEF (△ LVEF)in group A was significantly larger [△ LVEF:(-5.4 ± 7.3) ％ vs (2.5 ± 5.9) ％,P ＜ 0.05] than those of group B ; the absolute increase in LVEDD (△ LVEDD) in group A was significantly larger [△ LVEDD:(4.7 ± 3.1) mm vs (2.8 ± 4.2)mm,P ＜ 0.05] than those of group B ; the absolute increase in QRSd (△ QRSd) was significantly larger [△QRSd:(26.6±11.9)msvs (14.4±9.6)ms.P ＜ 0.05]than those of group B.Conclusions Frequent right ventricular apical pacing increases the risk of new-onset of heart failure in patients with single-chamber pacemaker implantation,and regularly program the pacemaker to decrease the right ventricular apical pacing as far as possible can delay the occurrence of heart failure.Key words: Right ventricular apical pacing; Heart failure; Left ventricular end-diastolic diameter; QRS duration" @default.
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- W3032255323 date "2013-05-25" @default.
- W3032255323 modified "2023-09-23" @default.
- W3032255323 title "Effects of right ventricular apical pacing on heart function in patients with single-chamber pacemaker implantation" @default.
- W3032255323 doi "https://doi.org/10.3760/cma.j.issn.1674-4756.2013.10.009" @default.
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