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- W3032256480 abstract "ObjectiveTo investigate the correlation between vascular endothelial growth factor (VEGF) gene+ 450 c/G polymorphism and psoriasis.MethodsSearching PubMed, Embase, the Cochrane Library, China academic journal full-text database, VIP database and Wanfang database, according to the inclusion and exclusion criteria included the research, and evaluated the quality of research, the Meta-analysis was performed by Stata 12.0.ResultsSix case-control studies were included. Meta analysis results showed that there was no correlation between the VEGF+ 405 c/G genotype and psoriasis susceptibility in total population (P>0.05). Subgroup analysis showed that the differences of genotype CC vs. GG, CC+ (CG) vs. GG with psoriasis susceptibility were significant in Asians(P>0.05). The publication bias were tested Begg’s inspection, all genotypes had no publication bias(P>0.05).ConclusionsVEGF+ 450 C/G gene may be correlated with psoriasis susceptibility in Asians.Key words: Psoriasis; Vascular endothelial growth factor; Gene polymorphism; Meta-analysis" @default.
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- W3032256480 date "2017-01-25" @default.
- W3032256480 modified "2023-09-23" @default.
- W3032256480 title "A meta-analysis of vascular endothelial growth factor gene+ 450 C/G polymorphism and psoriasis" @default.
- W3032256480 doi "https://doi.org/10.3760/cma.j.issn.1674-4756.2017.02.018" @default.
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