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- W3032277048 abstract "ObjectiveTo measure right ventricular longitudinal strain (RVLS) of pulmonary hypertension(PH) patients by two-dimensional speckle tracking echocardiography, and explore its clinical application value on evaluating right ventricular function and hemodynamics in PH.MethodsA total of 66 patients diagnosed as PH by right-heart catheterization were divided into Group I(WHO FCⅠ/Ⅱ) and Group II(WHO FC Ⅲ/Ⅳ) according to WHO pulmonary hypertension function classification. The right ventricular function parameters included: global right ventricular longitudinal strain (RVLSglobal), free-wall right ventricular longitudinal strain (RVLSFW), tricuspid annular plane systolic excursion (TAPSE), right ventricular fractional area change (FAC), tissue Doppler-derived tricuspid lateral annular systolic velocity (s′) and right ventricular index of myocardial performance (RIMP). Systolic pulmonary artery pressure (sPAP) was calculated through tricuspid regurgitation pressure gradient. Hemodynamic parameters include: mean pulmonary arterial pressure (mPAP), pulmonary vascular resistance (PVR), pulmonary capillary wedge pressure (PCWP) and cardiac index (CI).Results①Compared with Group Ⅰ, Group Ⅱ presented with higher sPAP (P<0.05). There also were significant differences between two groups in RVLSglobal, RVLSFW (P<0.01) and conventional right ventricular function parameters: TAPSE, RIMP and s′ (P<0.05). ②mPAP, PVR and CI had significant difference between two groups (P<0.01), while PCWP had no significant difference. mPAP and PVR increased more remarkable and CI decreased more significant in Group Ⅱ. ③RVLSglobal had positive correlation with mPAP (r=0.646, P=0.000) and PVR (r=0.628, P=0.000) measured by right-heart catheterization; RVLSFW also had positive correlation with mPAP (r=0.652, P=0.000) and PVR (r=0.634, P=0.000).ConclusionsRight ventricular longitudinal strain could evaluate the degree of decrease in right ventricular function of PH patients and reflex the change of hemodynamics at the same time, which may offer more reliable information to clinical treatment.Key words: Speckle tracking imaging; Pulmonary hypertension; Ventricular function, right; Hemodynamics" @default.
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- W3032277048 date "2016-07-25" @default.
- W3032277048 modified "2023-09-24" @default.
- W3032277048 title "Value of longitudinal strain of right ventricular by 2-dimensional speckle-tracking echocardiography in detecting right ventricular function and hemodynamics in pulmonary hypertension" @default.
- W3032277048 doi "https://doi.org/10.3760/cma.j.issn.1004-4477.2016.07.001" @default.
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