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- W3032297693 abstract "Colorectal Cancer (CRC) is a kind of molecular diversified neoplasm. For non-metastatic early CRC patients who received surgery based systemic treatment, the 5 years survival rate is as high as 50%-80%. However, only chemotherapy is available for majority of metastatic advanced CRC patients. The effect of chemotherapy is disappointing. Numerous studies have demonstrated that some patients with metastatic advanced CRC can benefit from anti-EGFR and anti-VEGF monoclonal antibodies. Here, we give a brief overview about the clinical research of the detection of KRAS, BRAF, MSI and HER2 in guiding treatment with targeted drugs in metastatic advanced CRC(Chin J Lab Med, 2017, 40: 326-330)Key words: Colorectal neoplasms; Molecular targeted therapy; Antibodies, monoclonal, humanized; Receptor, epidermal growth factor; Tumor markers, biological" @default.
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- W3032297693 date "2017-04-11" @default.
- W3032297693 modified "2023-09-26" @default.
- W3032297693 title "Recent advances in biomarkers for the targeted therapy of metastatic colorectal cancer" @default.
- W3032297693 doi "https://doi.org/10.3760/cma.j.issn.1009-9158.2017.04.023" @default.
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