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- W3032306223 abstract "Objectives Results from the related published studies on PSCA polymorphisms and cancer risk were somewhat underpowered in general.To assess the role of PSCA exon 1 C ＞ T variant in global cancer by meta-analysis.Methods A computerized literature search was conducted from PubMed and MEDLINE database.Two investigators extracted the data and reached a consensus on all items independently.Results The results showed evidence that PSCA exon 1 C ＞ T pymorphism was associated with increased total cancer risk in the overall comparisons.PSCA exon 1 C ＞T polymorphism has an increased risk in bladder cancer (P ＜0.001,OR =1.09,95％CI:1.05～1.13) and gastric cancer (P =0.006,OR=1.21,95％CI:1.06～1.39).Conclusions Thismeta-analysis showed evidence that PSCA exon 1 C ＞ T polymorphism was associated with bladder cancer and gastric cancer.Key words: Prostate-Specific Stem Cells; Antigen; Meta-Analysis; Polymorphism, Genetic" @default.
- W3032306223 created "2020-06-05" @default.
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- W3032306223 date "2013-05-15" @default.
- W3032306223 modified "2023-09-24" @default.
- W3032306223 title "PSCA exon 1 C ＞ T polymorphism and cancer risk : a meta-analysis" @default.
- W3032306223 doi "https://doi.org/10.3760/cma.j.issn.1673-4416.2013.03.006" @default.
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