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- W3032322689 abstract "目的 探讨低分子肝素对糖尿病大鼠肾脏的保护作用.方法 将实验动物随机分为正常对照组、糖尿病组以及低分子肝素治疗组.低分子肝素治疗组给予低分子肝素(1 mg·kg-1·d-1)治疗.8周后检测各组大鼠尿蛋白排泄率、血糖、血脂以及PT与KPTT,测定血浆P-selectin表达水平,观察组织病理学变化.结果 低分子肝素治疗组尿蛋白排泄率(P＜0.01)、高凝程度(P＜0.05)、血脂水平(P＜0.01)以及P-selectin表达(P＜0.01)均低于糖尿病组,肾组织病理改变亦明显较轻.结论 低分子肝素对2型糖尿病大鼠肾脏有保护作用,可能与抑制P-selectin的表达有关。" @default.
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- W3032322689 date "2006-10-10" @default.
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- W3032322689 title "Experimental study of low molecular weight heparin on renal protection in diabetic rats" @default.
- W3032322689 doi "https://doi.org/10.3760/cma.j.issn.1008-1372.2006.10.007" @default.
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