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- W3032328519 abstract "目的 探讨肝豆状核变性合并中央桥脑髓鞘溶解症(CPM)的MRI表现及弥散加权成像(DWI)的应用价值.方法采用1.5 T MR仪对2例肝豆状核变性合并CPM患者进行T1WI、T2WI、液体衰减反转恢复成像(FLAIR)、DWI和增强扫描MR检查.结果桥脑中央部、双侧豆状核、尾状核、丘脑等部位出现对称性长T1、T2信号,增强MRI无明显强化反应.DWI显示桥脑病变呈明显高信号,表观弥散系数(ADC)值在100×10 mm2/s～300×10-6mm2/s之间,FLAIR仅显示为略微高信号,表明病变伴有明显的细胞毒性水肿;同时,双侧肝豆状核亦表现出DWI高信号,ADC值在300×10-6mm2/s～600×10-6 mm2/s之间,FLAIR呈不均匀较高信号,其中1例尚出现尾状核头对称性DWI略低信号,表明在缓慢的病程进展中同时伴有细胞毒性水肿和血管源性水肿等改变.结论肝豆状核变性和CPM具有较为特征的MRI表现,DWI对其具有较大的诊断和鉴别诊断价值。" @default.
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- W3032328519 date "2004-07-10" @default.
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- W3032328519 title "MRI manifestation of Wilson′s disease accompanied with central pontine myelinolysis" @default.
- W3032328519 doi "https://doi.org/10.3760/j.issn:1005-1201.2004.07.018" @default.
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