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- W3032332926 abstract "Objective To observe the effect of alprostadil combined with tripterygium glycosides tablet on diabetic nephropathy.Methods Seventy-five patients with diabetic nephropathy were randomly divided into control group,alprostadil group and combination group (with alprostadil and tripterygium glycosides tablet added on the basis of the control group).The changes of the 24 h urinary protein,serum albumin,renal function,liver function,blood routine before treatment and 6,12 weeks after the treatment were observed,and the side effects of drugs were observed.Results Twenty-four hours urinary protein quantitative had no significant difference among the three groups before treatment (P ＞0.05); After 6,12weeks of treatment,the urine protein were lower than those before treatment,and the two treatment groups had significant differences (P ＜ 0.01),but the control group had no significant difference (P ＞ 0.05).Compared with the control group,there was significant difference in treatment group after 6 weeks treatment (P ＜0.05),and there were obviously differences in treatment group after 12 weeks treatment (P ＜0.01).The changes of other indicators of serum albumin,serum creatinine had no significant differences.Conclusions Alprostadil combined with tripterygium glycosides tablet is very effective on DN proteinuria,which can significantly reduce proteinuria in patients with DN,thus delay the progression of renal function.Key words: Alprostadil; Tripterygium glycosides tablet; Diabetic nephropathy" @default.
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- W3032332926 date "2014-05-25" @default.
- W3032332926 modified "2023-09-26" @default.
- W3032332926 title "Clinical research on alprostadil combined with tripterygium glycosides tablet in treating diabetic nephropathy proteinuria" @default.
- W3032332926 doi "https://doi.org/10.3760/cma.j.issn.1674-4756.2014.10.021" @default.
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