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- W3032347313 abstract "Calcific aortic valve disease (CAVD)was once recognized as a passive degenerative disease, but it has recently been shown to be an active process predominately regulated by valvular interstitial cells (VICs), which maintain the integrity of heart valve. In vitro culture of aortic VICs will lead to phenotypic switching into osteoblast-like cells and form calcific nodules, which can be influenced by multiple extrinsic factors. This paper provides a systematical overview of established in vitro models of CAVD.Key words: Calcific aortic valve disease; Valvular interstitial cells; Model" @default.
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- W3032347313 date "2018-05-08" @default.
- W3032347313 modified "2023-09-23" @default.
- W3032347313 title "Advances in cell models of calcific aortic valve disease" @default.
- W3032347313 doi "https://doi.org/10.3760/cma.j.issn.1001-9030.2018.05.061" @default.
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