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- W3032362980 abstract "Hirschsprung′s disease(HSCR) is a kind of complex digestive system disease with structural abnormalities, implicated a genetic, polygenic, multifactorial disease.Etiology and pathogenesis of HSCR are not clear, now research shows there is complex, multiple and abnormal signal transduction with development of HSCR.The variable phenotypic of HSCR may be the result of some gene mutation interfering with ganglion cell migration in signal pathway.Recently study has found that there are several signal transduction pathways strongly relevant to HSCR.Now, the research progress in primarily signal pathways relevant to HSCR were reviewed.Key words: Hirschsprung′s disease; Gene mutation; Signal pathway" @default.
- W3032362980 created "2020-06-05" @default.
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- W3032362980 date "2018-06-20" @default.
- W3032362980 modified "2023-09-27" @default.
- W3032362980 title "Research progress on signal pathways relevant to Hirschsprung′s disease" @default.
- W3032362980 doi "https://doi.org/10.3760/cma.j.issn.2095-428x.2018.12.022" @default.
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