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- W3032367445 abstract "ObjectiveTo understand the treatment patterns for bipolar disorders in China in 2006.MethodsBased on the economic level, 760 out- and in-patients, aged 16-65 years and meeting the ICD-10 criteria for bipolar disorder were selected from 41 hospitals in 10 provinces and municipalities using the convenient sampling. The investigation was conducted during 22th-28th May, 2006, using the retested and revised self-made modified questionnaires.Results(1) Totally 760 cases including 329 (43.3%) outpatients and 431(56.7%) inpatients (male: female=436∶318, missing value was 6) were recruited in the study. (2) Two thirds of patients experienced elation (n=481, 63.3%), flight of thought (n=436, 57.4%) and hyperactivity (n=513, 67.5%), and 21.3% patients (n=162) were bipolar depression. And 7.9% (n=60) of patients experienced psychotic symptoms, and 6.3% of them (n=48) manifested suicide idea or behaviors.More inpatients were severe and in the acute phase than outpatients. (3) 88.3% of the patients were treated with mood stabilizer, most frequently prescribed were lithium and valproate. The antipsychotics were used in 78% of all the patients, with the most five medications being clozapine, risperidone, chlorpromazine, quetiapine and haloperidone.18.7% (n=142) of the patients were prescribed antidepressants, the first-line drugs were SSRIs. (4) More inpatients were treated with the antipsychotics and more outpatients with antidepressants. (5) 79.8% of patients (n=606) were treated with two or more kinds of medications, with first-line strategy of combination of antipsychotics and mood stabilizers. (6) Results from the logistic analysis showed that the clinical profile, including experiencing psychotic symptoms, depressive or manic moods played the important role in using the antipsychotics, mood stabilizers or antidepressants treatment.ConclusionThe polypharmacy is the mainstream in treatment of bipolar disorder, with the combination of antipsychotics and mood stabilizers being the first-line choice. The prescription pattern for bipolar disorder is correlated to clinical characteristics of patients.Key words: Bipolar disorder; Sampling studies; Prescription，drug" @default.
- W3032367445 created "2020-06-05" @default.
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- W3032367445 date "2012-02-05" @default.
- W3032367445 modified "2023-09-23" @default.
- W3032367445 title "A cross-sectional study on treatment patterns of bipolar disorders in China in 2006" @default.
- W3032367445 doi "https://doi.org/10.3760/cma.j.issn.1006-7884.2012.01.012" @default.
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