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- W3032369769 abstract "Objective To study the efficacy and adverse effects of combination chemotherapy regimen including homoharringtonine and cytarabine in the treatment of chronic-phase of chronic myelogenous leukemia.Methods Thirty-six cases of chronic-phase chronic myelogenous leukemia had received 5 days or 7 days course of combination chemotherapy regimen homoharringtonine and cytarabine.Their spleen size,cytogenetic responses and adverse effects were observed.Results The complete remission(CR) rate studied Was 50.0% and 61.1% in 5 days' and 7 days' treated groups.The incidence of severe bonemarrow depression in 7 days' group(16.7%) was higher than that in 5 days' group(0.0%)(P＜0.05).Conclusion The combination chemotherapy HA resimen had curative effects in chronic-phase chronic myelogenous leukemia therapy while the incidence of severe bonemarrow depression in 7 days' group(16.7%) was higher than that in 5 days' group(P＜0.05).Key words: Chronic-phase chronic myelogenous leukemia; Combination chemotherapy regimen homoharringtonine and cytarabine; Curative effect" @default.
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- W3032369769 date "2009-08-25" @default.
- W3032369769 modified "2023-09-24" @default.
- W3032369769 title "Clinical study of combination chemotherapy regimen homoharringtonine and cytarabine for the curative effect on CML in chronic phase" @default.
- W3032369769 doi "https://doi.org/10.3760/cma.j.issn1673-8799.2009.08.28" @default.
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