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- W3032379481 abstract "ObjectiveTo compare the efficacy and safety of direct thrombectomy and bridging therapy for acute large-vessel occlusion in anterior circulation stroke.MethodsA retrospective study was performed on clinical data of 146 patients with anterior circulation large-vessel occlusion stroke who accepted direct thrombectomy in our hospital from March 2016 to July 2017; 85 patients were in direct thrombectomy group and 61 patients were in bridging therapy group. The clinical characteristics, procedural complications and clinical outcomes between the two groups were compared.ResultsThere were no significant differences between the two groups in age, gender, baseline National Institutes of Health Stroke Scale (NIHSS) scores, percentages of patients with hypertension, diabetes and atrial fibrillation, baseline blood glucose, platelet count, creatinine level, baseline systolic blood pressure, stroke etiology, occlusion site, and anesthesia methods (P>0.05). There were no significant differences between the two groups in admission-to-CT time, admission-to-puncture time, puncture-to-re-canalization time, and admission-to-re-canalization time (P>0.05). The successful reperfusion rate (91.8% vs. 95.1%), incidence of symptomatic intracranial hemorrhage (11.8% vs. 21.3%), favorable outcome rate 90 d after treatment (41.2% vs. 47.5%), and mortality (20.0% vs. 18.0%) were not significantly different between the two groups (P>0.05).ConclusionThe efficacy and safety of direct thrombectomy and bridging therapy are similar for acute large-vessel occlusion in anterior circulation stroke.Key words: Stroke; Direct thrombectomy; Bridging therapy" @default.
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- W3032379481 date "2018-10-15" @default.
- W3032379481 modified "2023-09-23" @default.
- W3032379481 title "Comparative study of efficacy and safety of direct thrombectomy and bridging therapy for acute large-vessel occlusion in anterior circulation stroke" @default.
- W3032379481 doi "https://doi.org/10.3760/cma.j.issn.1671-8925.2018.10.006" @default.
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