Matches in SemOpenAlex for { <https://semopenalex.org/work/W3032494171> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W3032494171 endingPage "123" @default.
- W3032494171 startingPage "121" @default.
- W3032494171 abstract "ObjectiveTo investigate the efficacy of duloxetine combined with small dose aripiprazole on senile somatization disorder.MethodsSeventy patients with somatization disorder were selected and were divided into experimental group and control group according to the random number table method, with 35 cases in each group. Patients in experimental group were treated with duloxetine enteric coated tablets and small doses of aripiprazole tablets. Patients in control group were treated with duloxetine enteric coated tablets only. All the patients were observed for 8 weeks. The patient health questionnaire-15 (PHQ-15) were used to evaluate the therapeutic effect before treatment and at the second and eighth week after treatment. The adverse reactions were evaluated by the treatment emergent symptom scale (TESS). The levels of blood pressure, blood sugar, blood lipid, blood routine, liver function, renal function, body mass index and electrocardiogram were monitored before treatment and 8 weeks after treatment.ResultsThree cases (8.57%) dropped out from experimental group and 4 cases (11.43%) dropped out from control group, the difference between the two groups was not statistically significant (χ2=2.67, P>0.05). The PHQ-15 scores of the two groups decreased at the second and eighth weekend, the difference was statistically significant (P<0.05), but the score of experimental group decreased more significantly (P<0.01). The incidence of adverse reactions in experimental group (6.25%) was lower than that in control group (16.13%), the difference was statistically significant (χ2=4.06, P<0.05). At the eighth week after treatment, 1 case (3.13%) had elevated blood glucose, 2 cases (6.25%) had elevated blood lipids, 1 case (3.13%) had elevated body mass index (BMI), and there was no other abnormal phenomena in experimental group. In control group, 3 cases (9.68%) had elevated blood glucose, 3 cases (9.68%) had elevated blood lipid, and 2 cases (6.45%) had elevated BMI, and there was no other abnormal phenomenon; the differences between the two groups were statistically significant (χ2=7.01, 7.53, 8.09, all P<0.01).ConclusionsThe efficacy of duloxetine combined with low dose aripiprazole in the treatment of somatization disorder is remarkable, of which the incidence of adverse reactions and metabolic syndrome is lower. It is worthy of further promotion.Key words: Duloxetine; Aripiprazole; Senile; Somatization disorder" @default.
- W3032494171 created "2020-06-05" @default.
- W3032494171 creator A5056788729 @default.
- W3032494171 date "2018-05-10" @default.
- W3032494171 modified "2023-09-23" @default.
- W3032494171 title "Efficacy of duloxetine combined with small dose aripiprazole on senile somatization disorder" @default.
- W3032494171 doi "https://doi.org/10.3760/cma.j.issn.1674-4756.2018.09.040" @default.
- W3032494171 hasPublicationYear "2018" @default.
- W3032494171 type Work @default.
- W3032494171 sameAs 3032494171 @default.
- W3032494171 citedByCount "0" @default.
- W3032494171 crossrefType "journal-article" @default.
- W3032494171 hasAuthorship W3032494171A5056788729 @default.
- W3032494171 hasConcept C118552586 @default.
- W3032494171 hasConcept C120665830 @default.
- W3032494171 hasConcept C121332964 @default.
- W3032494171 hasConcept C126322002 @default.
- W3032494171 hasConcept C134362201 @default.
- W3032494171 hasConcept C142724271 @default.
- W3032494171 hasConcept C197934379 @default.
- W3032494171 hasConcept C204787440 @default.
- W3032494171 hasConcept C2776412080 @default.
- W3032494171 hasConcept C2777631960 @default.
- W3032494171 hasConcept C2780211496 @default.
- W3032494171 hasConcept C2780764818 @default.
- W3032494171 hasConcept C42219234 @default.
- W3032494171 hasConcept C61511704 @default.
- W3032494171 hasConcept C71924100 @default.
- W3032494171 hasConcept C90924648 @default.
- W3032494171 hasConceptScore W3032494171C118552586 @default.
- W3032494171 hasConceptScore W3032494171C120665830 @default.
- W3032494171 hasConceptScore W3032494171C121332964 @default.
- W3032494171 hasConceptScore W3032494171C126322002 @default.
- W3032494171 hasConceptScore W3032494171C134362201 @default.
- W3032494171 hasConceptScore W3032494171C142724271 @default.
- W3032494171 hasConceptScore W3032494171C197934379 @default.
- W3032494171 hasConceptScore W3032494171C204787440 @default.
- W3032494171 hasConceptScore W3032494171C2776412080 @default.
- W3032494171 hasConceptScore W3032494171C2777631960 @default.
- W3032494171 hasConceptScore W3032494171C2780211496 @default.
- W3032494171 hasConceptScore W3032494171C2780764818 @default.
- W3032494171 hasConceptScore W3032494171C42219234 @default.
- W3032494171 hasConceptScore W3032494171C61511704 @default.
- W3032494171 hasConceptScore W3032494171C71924100 @default.
- W3032494171 hasConceptScore W3032494171C90924648 @default.
- W3032494171 hasIssue "9" @default.
- W3032494171 hasLocation W30324941711 @default.
- W3032494171 hasOpenAccess W3032494171 @default.
- W3032494171 hasPrimaryLocation W30324941711 @default.
- W3032494171 hasRelatedWork W1980058719 @default.
- W3032494171 hasRelatedWork W2168188592 @default.
- W3032494171 hasRelatedWork W2351472489 @default.
- W3032494171 hasRelatedWork W2354722959 @default.
- W3032494171 hasRelatedWork W2367139414 @default.
- W3032494171 hasRelatedWork W2367758103 @default.
- W3032494171 hasRelatedWork W2371332192 @default.
- W3032494171 hasRelatedWork W2375194610 @default.
- W3032494171 hasRelatedWork W2376066032 @default.
- W3032494171 hasRelatedWork W2377732283 @default.
- W3032494171 hasRelatedWork W2379360392 @default.
- W3032494171 hasRelatedWork W2380865011 @default.
- W3032494171 hasRelatedWork W2406626635 @default.
- W3032494171 hasRelatedWork W2977870944 @default.
- W3032494171 hasRelatedWork W2996038697 @default.
- W3032494171 hasRelatedWork W3025434724 @default.
- W3032494171 hasRelatedWork W3028871721 @default.
- W3032494171 hasRelatedWork W3032021759 @default.
- W3032494171 hasRelatedWork W3032231189 @default.
- W3032494171 hasRelatedWork W3202648063 @default.
- W3032494171 hasVolume "45" @default.
- W3032494171 isParatext "false" @default.
- W3032494171 isRetracted "false" @default.
- W3032494171 magId "3032494171" @default.
- W3032494171 workType "article" @default.