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- W3032496922 abstract "ObjectiveTo observe the effect of alprostadil on hemorrheological indicators of patients with multiple lacunar infarcts.Methods146 cases with multiple lacunar infarcts were randomly divided into observation group(76 cases) and control group(70 cases) by using the method of random number table.The two groups were given conventional treatment.In addition to this, the observation group was treated with alprostadil.NIHSS was used to evaluate neurological deficits, MMSE was used to evaluate cognitive function.The indicators of hemorheology and nailfold microcirculation integral were detected, adverse drug reactions of the two groups were observed.ResultsAfter treatment, the MMSE scores of the two groups [(24.09±3.88)points, (22.41±4.06)points] were significantly higher than before treatment, the NIHSS scores [(3.67±1.39)points, (4.35±1.62)points] decreased significantly (t=7.241, 21.095, 6.017, 14.179, all P 0.05).ConclusionIn the treatment of multiple lacunar infarcts, alprostadil can effectively improve hemorrheological and nailfold microcirculation integral indicators, improve the nerve defect and cognitive function of patients, the incidence rate of adverse reaction is low, it has high value in clinical application.Key words: Brain infarction; Alprostadil; Prostaglandin E1; Hemorheology" @default.
- W3032496922 created "2020-06-05" @default.
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- W3032496922 date "2017-12-01" @default.
- W3032496922 modified "2023-09-23" @default.
- W3032496922 title "Effect of alprostadil on hemorrheological indicators of patients with multiple lacunar infarcts" @default.
- W3032496922 doi "https://doi.org/10.3760/cma.j.issn.1008-6706.2017.23.023" @default.
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