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- W3032516395 abstract "目的:评价普拉洛芬滴眼液(pranoprofen)控制LASEK(准分子激光上皮角膜磨镶术,laser epithelial keratomileusis)术后疼痛及炎症反应的疗效和安全性.方法:采用随机对照试验,试验组滴用普拉洛芬滴眼液,每日3次,加氟美瞳滴眼液,每日4次,对照组单滴用氟美瞳滴眼液,每日4次.观察两组患者畏光、流泪、异物感、疼痛以及裂隙灯观察的情况,每项指标均按由轻到重分为无(0分)、轻(1分)、中(2分)、重(3分)和极重(4分)五级,各项指标得分相加后得到综合评分,比较两组在术前、术后1 d、术后4 d、术后7 d及术后14 d的综合评分差异.结果:共62例115眼完成试验,平均年龄为(26.46±6.56)岁.平均屈光度为(-5.75±2.25)D.试验组和对照组术后综合评分在术后第1天分别为5.84±2.81和8.84±2.41(P<0.001),第4天分别为0.90±1.12和4.67±2.51(P<0.001),差别均有显著性.第7天分别为0.10±0.31和0.16±0.37(P=0.39),第14天分别为0.034±0.19和0.02±0.13(P=0.57),差别均无显著性.症状消失的天数分别为(2.41±0.63)d和(3.84±0.75)d(P<0.001),差别有显著性.试验组未见严重并发症和副作用.结论:普拉洛芬滴眼液对于控制LASEK术后疼痛及炎症反应有效而安全。" @default.
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- W3032516395 date "2004-09-01" @default.
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- W3032516395 title "Clinical assessment of proanoprefen eyedrops on postoperative inflammation from LASEK" @default.
- W3032516395 doi "https://doi.org/10.3760/cma.j.issn.1008-1801.2004.03.005" @default.
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