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- W3032517322 abstract "Objective To evaluate the safety of the absorbed diphtheria,tetanus and acellular pertusis combined vaccine(DTaP),and provide the evidence for decision-making on National Immunization Program (NIP).Methods There were 3235 aged 3-5 months healthy children and 3198 aged 18-24 months healthy children in four counties in Zhejiang Province selected to immunize the DTaP according to the schedule of NIP.Adverse Events Following Immunization (AEFI) for each vaccinated child was observed.Results The incidence rates of AEFI for three primary doses and one boost dose were 6.28％,6.39％,6.26％ and 14.57％,respectively.There was no statistical difference among the rates of 3 primary doses vaccinated children,and the rate of one boost dose vaccinated children was significant higher than the average rate(6.31％ ) of basic vaccinated children ( x2 =1049,P ＜ 0.01 ).Most of the AEFI happened in 30 minutes after vaccinated.The main clinical character were fever,tetter and pain.Most of the AEFI were mild.There were not any rare,sever AEFI or new AEFI detected.Conclusions The reported AEFIs for DTaP were mild in this study.DTaP have a good immunization safety.Key words: Diphtheria-tetanus-pertussis vaccine; Acellular vaccines; Safety" @default.
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- W3032517322 date "2012-08-25" @default.
- W3032517322 modified "2023-09-26" @default.
- W3032517322 title "Research on the safety of the absorbed diphtheria, tetanus,and acellular pertusis combined vaccine(DTaP)" @default.
- W3032517322 doi "https://doi.org/10.3760/cma.j.issn.1673-4149.2012.04.004" @default.
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