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- W3032577065 abstract "对2006年2月16日新英格兰医学杂志(NEJM)发表的补充钙和维生素D与骨折危险一文进行评述.这是一项大样本的随机、对照临床试验,评价绝经后妇女长期补充钙和维生素D对预防骨质疏松性骨折的效果.结果显示,在健康的绝经后妇女中补充钙和维生素D后髋部骨密度少量增加,但未能显著减少髋部骨折的发生,而肾结石的危险增加.由于该研究在研究设计、人群的选择、依从性等方面存在明显的局限与缺陷,影响了研究结果的真实性、科学性和推广价值.本文的结论是:该研究没有提供充分可靠的证据否定补充钙和维生素D对防治骨质疏松的益处.基于以往的众多研究证据,继续推荐以钙和维生素D的适量补充作为防治骨质疏松的基础措施。" @default.
- W3032577065 created "2020-06-05" @default.
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- W3032577065 date "2006-07-20" @default.
- W3032577065 modified "2023-09-25" @default.
- W3032577065 title "Adequate supplementation of calcium and vitamin D is the essential strategy for prevention and treatment of osteoporosis" @default.
- W3032577065 doi "https://doi.org/10.3760/cma.j.issn.1673-4157.2006.04.001" @default.
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