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- W3032613832 abstract "目的 观察自体外周血造血干细胞移植(APBHSCT) 支持下大剂量化疗(HDC) 治疗晚期恶性肿瘤(MT) 的安全性及临床疗效.方法 将常规挽救化疗4个周期后获CR或PR的晚期或复发恶性肿瘤患者随机分组, 研究组26例行APBHSCT+HDC,对照组50例继续2～4个周期常规化疗.结果 研究组造血功能均重建,挽救化疗仅获PR的17例患者行APBHSCT+HDC后8例获CR,有效率为47.1%;对照组继续常规化疗后,33例PR的患者仍为PR.中位生存期研究组比对照组延长11个月(P＜0.05).2年、3年、4年生存率研究组比对照组明显提高(P＜0.05).结论 APBHSC+HDC治疗恶性肿瘤是一种安全有效的方法,可延长晚期或复发肿瘤患者的生存期和提高生存率。" @default.
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- W3032613832 date "2006-11-10" @default.
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- W3032613832 title "High-dose chemotherapy in patients with terminal malignant tumors supported by autologous peripheral blood stem cells transplantation" @default.
- W3032613832 doi "https://doi.org/10.3760/cma.j.issn.1008-1372.2006.11.014" @default.
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