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- W3032656906 abstract "Objective To evaluate the potential value of acoustic radiation force impulse (ARFI)elastography in the characterization of solid liver tumors.Methods Forty-three patients with 56 liver tumors were evaluated with ARFI,which included 21 patients with hepatocellular carcinoma (HCC),8 patients with metastase,5 patients with cholangiocarcinoma(CCC),and 9 patients with hemangioma.The shear wave velocity of the tumor and background liver parenchyma were calculated,and results were compared with 30 healthy subjects.Statistical analysis was performed on the shear wave velocity for differentiation of normal liver,background liver parenchyma,and tumors.Results HCC and CCC had greater stiffness than metastase (P ＜0.05),there were no statistical differences between HCC and CCC (P = 0.179).Malignant liver tumors had significantly greater stiffness than hemangioma and normal liver (P = 0.000).34.5% (9/26) HCC and 33.3% (4/12) hemangioma appeared softer than the background liver.With a cut-off value of 1.5 m/s for the shear wave velocity,the sensitivity,specificity,positive predictive value and negative predictive value for malignancies were 79.5%,83.3%,94.5% and 52.6%,respectively.Conclusions ARFI elastography quantification is a promising noninvasive technique for assessing solid liver tumors.Use of ARFI elastography quantification may lead to new quantitative tissue characterization parameters for differentiating hemangioma and malignant liver tumors.Key words: Ultrasonography; Liver neoplasms; Elasticity" @default.
- W3032656906 created "2020-06-05" @default.
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- W3032656906 date "2011-03-25" @default.
- W3032656906 modified "2023-09-28" @default.
- W3032656906 title "Initial study of acoustic radiation force impulse(ARFI) elastography quantification for evaluation of solid liver tumors" @default.
- W3032656906 doi "https://doi.org/10.3760/cma.j.issn.1004-4477.2011.03.015" @default.
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