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- W3032672497 abstract "Objective To investigate the effect of matrix metalloproteinase-9 (MMP-9) on the prognosis of transient ischemic attack(TIA). Methods Sixty-four patients with first-onset TIA(TIA group)and 64 age and sex matched cases without any cerebrovascular disease (control group) were involved in this study. The level of MMP-9 was measured by ELISA method,and the subsequent vascular events and death rate were determined in both groups over 4 years. Results The level of MMP-9 in TIA group was significantly higher than that in control group [(5.25 ± 0.51 ) μg/L vs. (3.25 ± 0.39 ) μg/L, t = 7.830, P 4.5 μg/L) was 2.612 (95% CI 1.557-5.463 ,P < 0.01 ) in TIA group. This increased relative risk for primary endpoint events in TIA group persisted after the adjustment for age, sex, body mass index, blood fat level and other cardiovascular risk factors such as hypertension, diabetes and smoking (OR =2.346,95% CI 1.418-5.216,P =0.006).Conclusions The level of MMP-9 in TIA patients has relationship with prognosis and inflammation may play an important role in TIA. MMP-9 may be a marker in predicting prognosis.Key words: Ischemic attack,transient; Matrix metalloproteinase 9; Prognosis" @default.
- W3032672497 created "2020-06-05" @default.
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- W3032672497 date "2010-09-05" @default.
- W3032672497 modified "2023-09-25" @default.
- W3032672497 title "The effect of matrix metalloproteinase-9 on the prognosis of transient ischemic attack" @default.
- W3032672497 doi "https://doi.org/10.3760/cma.j.issn.1673-4904.2010.25.008" @default.
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