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- W3032679106 abstract "ObjectiveTo compare the clinical effects of laparoscopic radical resection of colorectal cancer (LCR) and laparoscopic transluminal resection of colorectal cancer specimens (NOSE) in the treatment of colorectal cancer.MethodsThe data of patients with colorectal cancer who underwent surgical treatment from April 2013 to April 2018 were retrospectively analyzed. The patients were divided into NOSE group (63 cases underwent laparoscopic NOSE) and LCR group (63 cases underwent laparoscopic LCR). The software SPSS 19.0 was used for statistical analysis. Rehabilitation index comparison, oxidative stress index and inflammatory factors were described by (±s), independent t test, and incidence of complications by χ2 test. The difference was statistically significant with P<0.05.ResultsCompared with LCR group, the recovery indexes (exhaust time and hospitalization time) of NOSE group were significantly shorter (P < 0.05), oxidative stress indexes (MDA, SOD) were significantly higher (P<0.05) and SOD was significantly lower (P<0.05), but the SOD and MDA of NOSE group were lower than those of LCR group. Comparisons of CRP, TNF-a and IL-6 showed that the increase of NOSE group was lower than that of LCR group, and the incidence of complications in NOSE group was lower than that in LCR group (6.4% vs.19.1%), P<0.05.ConclusionCompared with traditional laparoscopic LCR, laparoscopic NOSE for colorectal cancer is effective in improving oxidative stress and inflammatory response, reducing the incidence of postoperative complications and facilitating rapid recovery.Key words: Colorectal neoplasms; Laparoscopes; Removal through natural cavity; Treatment outcome" @default.
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- W3032679106 date "2019-12-26" @default.
- W3032679106 modified "2023-09-26" @default.
- W3032679106 title "The clinical effect of NOSE in the treatment of colorectal cancer patients" @default.
- W3032679106 doi "https://doi.org/10.3877/cma.j.issn.1674-3946.2019.06.018" @default.
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