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- W3032687006 abstract "ObjectiveTo explore the feasibility of Guardian real-time continuous monitoring system(GRT) in high-risk infants with hypoglycemia.MethodsThe glucose of 72 infants admitted to Neonatal Intensive Care Unit(NICU) of Children′s Hospital of Fudan University between May 2015 and December 2016 were detected by GRT (provided by Medtronic), there were 43 males and 29 females with gestational age [(35.25±4.45) weeks], and birth weight [(2 385.69±1 062.63) g]. At the same time, the capillary glucose was monitored intermittently detected by using ACCU-CHEK®.ResultsA total of 1 134 paired glucose levels were collected.A good correlation between the paired capillary[(5.23±1.96) mmol/L] and GRT continuous monitor measurements [(5.19±1.99) mmol/L] was found(r=0.88, P 7.0 mmol/L.A high/low blood glucose detected by peripheral blood glucose monitoring is a high/low blood glucose event, and a high/low blood glucose detected by GRT in a continuous period is a high/low blood glucose event.Twelve cases of hypoglycemia, 26 episodes of hypoglycemia, 29 cases of hyperglycemia, and 151 episodes of hyperglycemia were detected by using fast blood glucose meter.Twenty-six cases of hypoglycemia, 88 episodes of hypoglycemia, 38 cases of hyperglycemia, and 229 episodes of hyperglycemia were detected by using GRT.Sixty-two episodes of hypoglycemia were not detected by the fast blood glucose meter, with 14 episodes lasting longer than 30 min, 4 longer than 60 min, and 5 longer than 90 min.There were 78 hyperglycemic episodes that were not detected by the fast blood glucose meter, with 44 episodes lasting longer than 30 min, 15 longer than 60 min, and 70 longer than 90 min.There were significant differences in the testing of hypoglycemia and pathoglycemia(χ2=7.00, 18.60; all P 0.05). GRT was acceptable to parents, medical staffs and children as only 3 infants bled when the continuous glucose sensor was imbedded, but there was no progressive increase in blood loss.There was no redness, edema, infections, or effusions at the insertion sites.ConclusionsThe use of GRT continuous monitoring system in high-risk infants of hypoglycemia was feasible.Compared with the conventional intermittent peripheral blood glucose monitoring, more abnormal blood glucose events and their duration could be detected.Key words: Hypoglycemia; Infants, newborn; Real-time continuous monitoring system" @default.
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- W3032687006 date "2019-01-05" @default.
- W3032687006 modified "2023-09-22" @default.
- W3032687006 title "The exploration of Guardian real-time continuous monitoring system in high-risk infants with hypoglycemia" @default.
- W3032687006 doi "https://doi.org/10.3760/cma.j.issn.2095-428x.2019.01.005" @default.
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