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- W3032724328 abstract "ObjectiveTo investigate the correlation between serum neutrophil gelatinase-associated lipocalin (NGAL) content and levels of serum ferritin (SF) and transferrin saturation (TSAT) in patients with type 2 diabetic nephropathy.MethodsFifty-two patients with type 2 diabetic nephropathy were selected and were divided into high-level serum NGAL group (level of serum NGAL>the median) and low-level serum NGAL group (level of serum NGAL≤the median) according to their serum NGAL median value, with 26 cases in each group. The related indicators levels of iron metabolism [SF, TSAT, total iron binding capacity (TIBC) and serum iron (Fe)] were compared between the two groups; and the correlations between serum NGAL content and serum SF, TSAT, TIBC and Fe levels in patients with type 2 diabetic nephropathy were analyzed.ResultsThe levels of serum SF, TSAT in high-level serum NGAL group were higher than those in low-level serum NGAL group, the difference was statistically significant (P 0.05). The Spearman correlation analysis showed that type 2 diabetic nephropathy was positively correlated with levels of serum NGAL, SF and TSAT (P<0.05).ConclusionsThe content of serum NGAL in type 2 diabetic nephropathy is positively correlated with levels of serum SF and TSAT, and corresponding expression detection can indirectly reflect the iron metabolism situation of patients.Key words: Type 2 diabetic nephropathy; Neutrophil gelatinase-associated lipocalin; Ferritin; Transferrin saturation" @default.
- W3032724328 created "2020-06-05" @default.
- W3032724328 creator A5006506906 @default.
- W3032724328 date "2018-03-10" @default.
- W3032724328 modified "2023-09-23" @default.
- W3032724328 title "Correlation between the content of serum NGAL and levels of serum SF and TSAT in patients with type 2 diabetic nephropathy" @default.
- W3032724328 doi "https://doi.org/10.3760/cma.j.issn.1674-4756.2018.05.013" @default.
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