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- W3032731261 abstract "目的探讨急性热暴露复合创伤后血浆一氧化氮(NO)早期变化及其对血压的可能影响,为急性应激条件下NO的作用机制研究提供理论依据.方法建立兔急性热暴露复合创伤模型,实验动物分为常温无创组、常温创伤组、高温无创组、高温创伤组.于0、1、2 h不同时间点取血测定NO含量,全程监测血压变化.结果急性热暴露创伤后1 h左右,兔血浆NO浓度下降,然后升高,高温创伤组NO浓度在1、2 h时分别为(42.75±8.24)、(59.54±9.05)μmol/L,差异有显著性(P＜0.05),而正常对照组则为(56.63±3.79)、(55.22±7.15)μmol/L,两组于1 h时的差异有显著性(P＜0.05).在高温和创伤条件下,兔平均动脉压(MAP)于60～70 min降至最低点,继之有一个短暂的回升,然后则迅速下降.结论急性热暴露复合创伤兔早期血浆NO浓度先降低后升高,且与MAP的变化有一定关系." @default.
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- W3032731261 date "2003-01-20" @default.
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- W3032731261 title "Effect of hyperthermia combined with trauma on serum nitric oxide and mean arterial pressure in rabbits" @default.
- W3032731261 doi "https://doi.org/10.3760/cma.j.issn.1001-9391.2003.01.009" @default.
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