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- W3032743402 abstract "在慢性氟中毒发病机制研究中,氧化应激一直是大家关注的热点之一[1].我们对这个问题曾做过综述[2,3].不久前印度学者Reddy等[4]曾报道他们在氟骨症病例和氟中毒家兔(饮水加氟化钠150 mg/L,6个月)的研究结果,在红细胞谷胱甘肽过氧化物酶(GSH-Px)、谷胱甘肽转硫酶(GST)、过氧化氢酶(CAT)及血浆维生素C(VC)、还原性谷胱甘肽(GSH)、丙二醛(MDA)等指标上,氟中毒与相应对照组之间未发现有明显差别.迄今在氟中毒与氧化应激研究方面所使用的指标主要是抗氧化酶GSHPx、GST、SOD(超氧化物歧化酶)、CAT,抗氧化剂VE (维生素E)、VC、GSH和反映机体脂质过氧化的LPO(脂质过氧化物)、MDA等几类,所得结果互有差异或相互矛盾,有待进行更深入的研究。" @default.
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- W3032743402 date "2005-01-20" @default.
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- W3032743402 title "Secondary discussion of chronical flurosis and oxidative stress" @default.
- W3032743402 doi "https://doi.org/10.3760/cma.j.issn.1000-4955.2005.01.002" @default.
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