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- W3032762778 abstract "ObjectiveTo study the relationship between smoking and plasma high-sensitivity C-reactive protein, lipoprotein(a)and blood lipid levels in male patients with acute coronary syndromes(ACS).MethodsA total of 181 male ACS patients were enrolled in the Department of Cardiology, PLA Wuhan General Hospital from January 2016 to January 2017, including three subgroups [66 patients with unstable angina pectoris(UAP), 60 patients with acute non-ST-elevation myocardial infarction(NSTEMI), and 55 patients with acute ST-elevation myocardial infarction(STEMI)]. History of smoking and alcohol consumption was collected; and levels of plasma hs-CRP, LP(a), lipids [triacylglycerol(TG), total cholesterol(TC), high density lipoprotein cholesterol(HDL-C), low density lipoprotein cholesterol(LDL-C)] were measured.The differences of hs-CRP, LP(a), serum lipids were compared among the non-smoking(Group A), quit-smoking(Group B), smoking(Group C), and ACS subgroups.Results(1)There was no significant difference in age, body mass index(BMI), alcohol consumption, systolic blood pressure, fasting blood glucose and glycosylated hemoglobin between group A, B and C(all P> 0.05); the levels of hs-CRP, HDL-C in group A, B and C were significantly different(all P 0.05); there was no significant difference between coronary angiography and stent in different smoking cases(all P>0.05). (2)Subgroup analysis showed that the levels of hs-CRP between the A, B, and C groups in NSTEMI and STEMI patients were statistically significant(P 0.05). There was no significant difference between UAP and NSTEMI patients(all P> 0.05).ConclusionsDifferent smoking conditions are closely related to male plasma hs-CRP, HDL-C levels in patients with ACS, regardless of LP(a), TG, TC, LDL-C levels; smoking can cause elevated hs-CRP levels and decreased HDL-C levels, and smoking cessation can greatly improve hs-CRP and HDL-C levels.Key words: Acute coronary syndrome; Smoking; High-sensitivity C-reactive protein; Lipoprotein(a); Cholesterol" @default.
- W3032762778 created "2020-06-05" @default.
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- W3032762778 date "2017-10-25" @default.
- W3032762778 modified "2023-09-23" @default.
- W3032762778 title "Correlation analysis of relationship between smoking and high-sensitivity C-reactive protein, lipoprotein(a)and blood lipids levels in male patients with acute coronary syndrome" @default.
- W3032762778 doi "https://doi.org/10.3969/j.issn.1007-5410.2017.05.006" @default.
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