Matches in SemOpenAlex for { <https://semopenalex.org/work/W3032783996> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W3032783996 endingPage "663" @default.
- W3032783996 startingPage "660" @default.
- W3032783996 abstract "Objective To detect the changes of peripheral blood T lymphocyte subsets in patients with hand,foot and mouth disease (HFMD) and investigate its clinical significance.Methods Three hundred and eighty-six patients with HFMD and 78 healthy children were detected the peripheral blood T lymphocyte subsets levels using the flow cytometry (FCM).The patients were divided into 325 common patients and 61 critically ill patients according to the severity of disease.Among the 386 patients,264 were in infection stage and 122 were in recovery stage.Compared the differences of peripheral blood T lymphocyte subsets levels in patients and healthy controls,common patients and critically ill patients,infection patients and recovery patients respectively.Results The patients' numbers of CD3 +,CD4 +,CD8 + cells and CD4 +/CD8 + ratio were (47.4 ± 10.6) ％,(24.0 ±8.0) ％,(23.2 ± 7.4) ％ and 1.0 ± 0.5 respectively.These parameters were significantly different with those in the control group ((68.4±7.5)％,(38.2 ±6.9)％,(18.8 ±4.6)％ and 2.0 ±0.4 respectively;t =3.16,4.62,2.23 and 2.51 respectively,P ＜ 0.05).The common patients' numbers of CD3 +,CD4 +,CD8 + cells and CD4+/CD8 + ratio were (53.0 ±9.8)％,(26.5 ±7.9)％,(20.4±7.5)％and 1.3 ±0.6,which had significant differences compared with those of the critically ill patients ((42.3 ± 10.9) ％,(18.7 ± 4.7) ％,(24.2 ± 7.4) ％ and (0.7 ± 0.4) respectively; t =2.25,2.47,1.91 and 2.32 respectively,P ＜ 0.05).The infection patients' CD3 +,CD4 +,cell numbers and CD4 +/CD8 + ratio were (45.3 ± 10.5) ％,(21.6 ± 8.4) ％and 0.9 ± 0.5.These parameters were significantly different with those of the recovery patients ((54.7 ±9.9)％,(27.5 ± 9.1)％ and 1.4 ± 0.6 respectively; t =2.41,1.87 and 2.92 respectively,P ＜ 0.05).Conclusion The cellular immunity of patients with HFMD was impaired.The T lymphocyte function was suppressed,and the level of suppression was positively correlated to severity of the illness.Key words: Hand,foot and mouth disease; Children; T lymphocyte subsets; Cellular immunity; Flow cytometry" @default.
- W3032783996 created "2020-06-05" @default.
- W3032783996 creator A5042456818 @default.
- W3032783996 creator A5065099550 @default.
- W3032783996 creator A5073086360 @default.
- W3032783996 date "2013-06-01" @default.
- W3032783996 modified "2023-09-23" @default.
- W3032783996 title "Studies on the changes and clinical significance of peripheral blood T lymphocyte Subsets in 386 Patients with Hand, Foot and Mouth Disease" @default.
- W3032783996 doi "https://doi.org/10.3760/cma.j.issn.1008-6315.2013.06.034" @default.
- W3032783996 hasPublicationYear "2013" @default.
- W3032783996 type Work @default.
- W3032783996 sameAs 3032783996 @default.
- W3032783996 citedByCount "0" @default.
- W3032783996 crossrefType "journal-article" @default.
- W3032783996 hasAuthorship W3032783996A5042456818 @default.
- W3032783996 hasAuthorship W3032783996A5065099550 @default.
- W3032783996 hasAuthorship W3032783996A5073086360 @default.
- W3032783996 hasConcept C114684123 @default.
- W3032783996 hasConcept C126322002 @default.
- W3032783996 hasConcept C167672396 @default.
- W3032783996 hasConcept C203014093 @default.
- W3032783996 hasConcept C2777761686 @default.
- W3032783996 hasConcept C2780218660 @default.
- W3032783996 hasConcept C3017910909 @default.
- W3032783996 hasConcept C3020391436 @default.
- W3032783996 hasConcept C46762472 @default.
- W3032783996 hasConcept C63363279 @default.
- W3032783996 hasConcept C71924100 @default.
- W3032783996 hasConcept C8891405 @default.
- W3032783996 hasConcept C90924648 @default.
- W3032783996 hasConceptScore W3032783996C114684123 @default.
- W3032783996 hasConceptScore W3032783996C126322002 @default.
- W3032783996 hasConceptScore W3032783996C167672396 @default.
- W3032783996 hasConceptScore W3032783996C203014093 @default.
- W3032783996 hasConceptScore W3032783996C2777761686 @default.
- W3032783996 hasConceptScore W3032783996C2780218660 @default.
- W3032783996 hasConceptScore W3032783996C3017910909 @default.
- W3032783996 hasConceptScore W3032783996C3020391436 @default.
- W3032783996 hasConceptScore W3032783996C46762472 @default.
- W3032783996 hasConceptScore W3032783996C63363279 @default.
- W3032783996 hasConceptScore W3032783996C71924100 @default.
- W3032783996 hasConceptScore W3032783996C8891405 @default.
- W3032783996 hasConceptScore W3032783996C90924648 @default.
- W3032783996 hasIssue "06" @default.
- W3032783996 hasLocation W30327839961 @default.
- W3032783996 hasOpenAccess W3032783996 @default.
- W3032783996 hasPrimaryLocation W30327839961 @default.
- W3032783996 hasRelatedWork W2349562119 @default.
- W3032783996 hasRelatedWork W2357987885 @default.
- W3032783996 hasRelatedWork W2359575921 @default.
- W3032783996 hasRelatedWork W2360208560 @default.
- W3032783996 hasRelatedWork W2363340727 @default.
- W3032783996 hasRelatedWork W2368371677 @default.
- W3032783996 hasRelatedWork W2373187964 @default.
- W3032783996 hasRelatedWork W2377171977 @default.
- W3032783996 hasRelatedWork W2377387200 @default.
- W3032783996 hasRelatedWork W2383951284 @default.
- W3032783996 hasRelatedWork W2386315356 @default.
- W3032783996 hasRelatedWork W2391413179 @default.
- W3032783996 hasRelatedWork W2391432128 @default.
- W3032783996 hasRelatedWork W2393035364 @default.
- W3032783996 hasRelatedWork W2393175485 @default.
- W3032783996 hasRelatedWork W2393366020 @default.
- W3032783996 hasRelatedWork W2404134529 @default.
- W3032783996 hasRelatedWork W2995516825 @default.
- W3032783996 hasRelatedWork W3029353409 @default.
- W3032783996 hasRelatedWork W3030246561 @default.
- W3032783996 hasVolume "29" @default.
- W3032783996 isParatext "false" @default.
- W3032783996 isRetracted "false" @default.
- W3032783996 magId "3032783996" @default.
- W3032783996 workType "article" @default.