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- W3032798402 abstract "ObjectiveTo evaluate the efficacy of oxycodone for intravenous analgesia after off-pump coronary artery bypass grafting(OPCABG).MethodsFifty patients scheduled for OPCABG were randomly divided into 2 groups (25 patients in each): received treatment with oxycodone (group Q) and sufentanil (group S). The patient-controlled intravenous analgesia (PCIA) with oxycodone or sufentanil was used for postoperative analgesia lasting for 48 h to maintain VAS<4. In group Q and S, PCIA was respectively achieved by infusing 100 mg oxycodone and 200 μg sufentanil with 12 mg tropisetron in 200 ml 0.9% sodium chloride solution. The PCIA pump was used to deliver a constant dosage of oxycodone at a rate of 0.5 mg/h with boluses of 2 mg oxycodone every 5 min in group Q, while to deliver sufentanil at a rate of 4 μg/h with boluses of 2 μg sufentanil every 10 min in group S. Pain VAS score at rest and during movement, sedation score, number of successful bolus and delivered dose, requirement for rescuing analgesic, and the adverse effects were assessed at 24 h and 48 h after administration. The levels of patient's satisfaction were recorded within 48 h after operation.ResultsThe ratio of adequate pain relief during movement 48 h after administration in group Q(89%) was higher than in group S (25%)(P 0.05).ConclusionsPCIA with oxycodone can produce satisfactory analgesic efficacy after OPCABG.Key words: Oxycodone; Analgesia, patient-controlled; Pain, postoperative; Coronary artery bypass" @default.
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- W3032798402 date "2018-01-15" @default.
- W3032798402 modified "2023-09-27" @default.
- W3032798402 title "Efficacy of oxycodone for intravenous analgesia after off-pump coronary artery bypass grafting" @default.
- W3032798402 doi "https://doi.org/10.3760/cma.j.issn.1673-4378.2018.01.009" @default.
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