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- W3032807800 abstract "目的探讨抗肿瘤坏死因子抗体(TNF-α Ab)对体外循环(CPB)肺损伤的保护作用.方法选择CPB瓣膜置换病人20例,随机分为对照组和用药组各10例.用药组于CPB前和主动脉开放后即刻经气管插管注入TNF-α Ab.测定两组围CPB期肺动态顺应性,左、右心房血中性粒细胞计数、肿瘤坏死因子(TNF-α)含量等指标.结果用药组CPB后各时点肺动态顺应性显著高于对照组;TNF-α Ab明显抑制肺源性TNF(COB)-α的释放及中性粒细胞在肺内的聚集.结论预防性应用TNF-α Ab对体外循环肺损伤有明显的保护作用." @default.
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- W3032807800 date "2003-05-25" @default.
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- W3032807800 title "The protective effect of tumor necrosis factor-αantibody on lung injury after cardiopulmonary bypass" @default.
- W3032807800 doi "https://doi.org/10.3760/cma.j.issn.1001-4497.2003.03.012" @default.
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