Matches in SemOpenAlex for { <https://semopenalex.org/work/W3032810366> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W3032810366 endingPage "391" @default.
- W3032810366 startingPage "389" @default.
- W3032810366 abstract "Objective To evaluate the effects of promethazine or dexamethasone pretreatment on histamine release induced by mivacurium in pediatric patients.Methods Eighty pediatric patients,of ASA physical status Ⅰ or Ⅱ,aged 4-10 yr,weighing 14-30 kg,scheduled for elective tonsillectomy and adenoidectomy,were randomized into 4 groups (n =20 each) using a random number table:rocuronium group (group R),mivacurium group (group M),dexamethasone + mivacurium group (group DM) and promethazine + mivacurium group (group PM).Dexamethasone 0.2 mg/kg and promethazine 0.5 mg/kg were injected intramuscularly at 60 min before anesthesia in DM and PM groups,respectively.Anesthesia was induced with midazolam,propofol,fentanyl and rocuronium 600 μg/kg (in group R) or mivacurium 200 μg/kg (in M,MD and MP groups).At 1 min before administration of muscle relaxants and 1,3 and 5 min after administration of muscle relaxants,MAP and HR were recorded,blood samples were taken from the radial artery for determination of plasma histamine concentrations,and the cutaneous adverse reactions were observed.Results Compared with group R,MAP was significantly decreased at T1-3,HR and plasma histamine concentrations were increased at Ti,2,and the grade of cutaneous adverse reactions was increased in group M,MAP was decreased at T1,2,HR was increased at T1-3,plasma histamine concentrations were increased at T1 in group DM,and plasma histamine concentrations were increased at T1 in group PM.Compared with group M,MAP was significantly increased at T2 in group DM,MAP was increased and HR was decreased at T1-3,plasma histamine concentrations were decreased at T1,2 in group PM,and the grade of cutaneous adverse reactions was decreased in DM and PM groups.Conclusion Promethazine pretreatment can decrease the mivacurium-caused release of histamine in pediatric patients,while dexamethasone pretreatment has no such effects.Key words: Dexamethasone ; Promethazine ; Ischemic preconditioning; Androstanols ; Histamine ; Child" @default.
- W3032810366 created "2020-06-05" @default.
- W3032810366 creator A5004491347 @default.
- W3032810366 creator A5029436410 @default.
- W3032810366 creator A5068070927 @default.
- W3032810366 creator A5076246631 @default.
- W3032810366 creator A5085038573 @default.
- W3032810366 creator A5089161437 @default.
- W3032810366 date "2014-04-20" @default.
- W3032810366 modified "2023-10-11" @default.
- W3032810366 title "Effects of promethazine or dexamethasone pretreatment on histamine release induced by mivacurium in pediatric patients" @default.
- W3032810366 doi "https://doi.org/10.3760/cma.j.issn.0254-1416.2014.04.002" @default.
- W3032810366 hasPublicationYear "2014" @default.
- W3032810366 type Work @default.
- W3032810366 sameAs 3032810366 @default.
- W3032810366 citedByCount "0" @default.
- W3032810366 crossrefType "journal-article" @default.
- W3032810366 hasAuthorship W3032810366A5004491347 @default.
- W3032810366 hasAuthorship W3032810366A5029436410 @default.
- W3032810366 hasAuthorship W3032810366A5068070927 @default.
- W3032810366 hasAuthorship W3032810366A5076246631 @default.
- W3032810366 hasAuthorship W3032810366A5085038573 @default.
- W3032810366 hasAuthorship W3032810366A5089161437 @default.
- W3032810366 hasConcept C1122143 @default.
- W3032810366 hasConcept C126322002 @default.
- W3032810366 hasConcept C2776277131 @default.
- W3032810366 hasConcept C2776814716 @default.
- W3032810366 hasConcept C2776988050 @default.
- W3032810366 hasConcept C2778000748 @default.
- W3032810366 hasConcept C2778794651 @default.
- W3032810366 hasConcept C2779073326 @default.
- W3032810366 hasConcept C2780401358 @default.
- W3032810366 hasConcept C2781072394 @default.
- W3032810366 hasConcept C42219234 @default.
- W3032810366 hasConcept C71924100 @default.
- W3032810366 hasConcept C98274493 @default.
- W3032810366 hasConceptScore W3032810366C1122143 @default.
- W3032810366 hasConceptScore W3032810366C126322002 @default.
- W3032810366 hasConceptScore W3032810366C2776277131 @default.
- W3032810366 hasConceptScore W3032810366C2776814716 @default.
- W3032810366 hasConceptScore W3032810366C2776988050 @default.
- W3032810366 hasConceptScore W3032810366C2778000748 @default.
- W3032810366 hasConceptScore W3032810366C2778794651 @default.
- W3032810366 hasConceptScore W3032810366C2779073326 @default.
- W3032810366 hasConceptScore W3032810366C2780401358 @default.
- W3032810366 hasConceptScore W3032810366C2781072394 @default.
- W3032810366 hasConceptScore W3032810366C42219234 @default.
- W3032810366 hasConceptScore W3032810366C71924100 @default.
- W3032810366 hasConceptScore W3032810366C98274493 @default.
- W3032810366 hasIssue "04" @default.
- W3032810366 hasLocation W30328103661 @default.
- W3032810366 hasOpenAccess W3032810366 @default.
- W3032810366 hasPrimaryLocation W30328103661 @default.
- W3032810366 hasRelatedWork W2124657361 @default.
- W3032810366 hasRelatedWork W2357773265 @default.
- W3032810366 hasRelatedWork W2359731700 @default.
- W3032810366 hasRelatedWork W2366495039 @default.
- W3032810366 hasRelatedWork W2373435826 @default.
- W3032810366 hasRelatedWork W2373893862 @default.
- W3032810366 hasRelatedWork W2374869414 @default.
- W3032810366 hasRelatedWork W2381165856 @default.
- W3032810366 hasRelatedWork W2381572498 @default.
- W3032810366 hasRelatedWork W2381618635 @default.
- W3032810366 hasRelatedWork W2398265961 @default.
- W3032810366 hasRelatedWork W2460772121 @default.
- W3032810366 hasRelatedWork W3029067225 @default.
- W3032810366 hasRelatedWork W3031058683 @default.
- W3032810366 hasRelatedWork W3031376651 @default.
- W3032810366 hasRelatedWork W3031695371 @default.
- W3032810366 hasRelatedWork W3031848476 @default.
- W3032810366 hasRelatedWork W3031910084 @default.
- W3032810366 hasRelatedWork W3032187169 @default.
- W3032810366 hasRelatedWork W3032887843 @default.
- W3032810366 hasVolume "34" @default.
- W3032810366 isParatext "false" @default.
- W3032810366 isRetracted "false" @default.
- W3032810366 magId "3032810366" @default.
- W3032810366 workType "article" @default.