Matches in SemOpenAlex for { <https://semopenalex.org/work/W3032830144> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W3032830144 endingPage "298" @default.
- W3032830144 startingPage "295" @default.
- W3032830144 abstract "目的 探讨白细胞介素(IL)1α、β mRNA和γ干扰素(IFN-γ)mRNA在子宫内膜异位症(内异症)患者异位和在位内膜巨噬细胞中的表达变化及意义.方法采用原位杂交技术检测40例内异症患者(内异症组)异位和在位内膜(增生期18例,分泌期22例)和15例子宫肌瘤患者(对照组)的内膜(增生期8例,分泌期7例)巨噬细胞中IL-1α、β和IFN-γmRNA表达水平.结果(1)内异症组患者异位、在位内膜及对照组内膜巨噬细胞中IL-1α mRNA阳性表达率分别为70%(28/40)、38%(15/40)和20%(3/15),表达水平分别为3.12±0.32、2.65±0.34、1.32±0.23;IL-1βmRNA阳性表达率分别为75%(30/40)、40%(16/40)和20%(3/15),表达水平分别为3.45±0.43、2.74±0.39、1.45±0.18;内异症组IL-1α、β mRNA的表达水平较对照组明显升高,内异症组异位内膜较在位内膜的表达水平也明显升高,差异均有统计学意义(P＜0.05).(2)内异症组在位内膜和对照组内膜巨噬细胞中IL-1α、β mRNA表达分泌期高于增生期,差异也有统计学意义(P＜0.05).(3)内异症组内膜巨噬细胞中IFN-γmRNA的表达水平与对照组比较,差异无统计学意义(P＞0.05),且无周期性变化.结论内异症患者在位内膜和异位内膜巨噬细胞IL-1表达明显增强,而IFN-γ表达则无明显变化,推测内膜巨噬细胞及其分泌的细胞因子,可能参与了内异症的发生、发展过程。" @default.
- W3032830144 created "2020-06-05" @default.
- W3032830144 creator A5008518733 @default.
- W3032830144 creator A5034068134 @default.
- W3032830144 creator A5064701888 @default.
- W3032830144 creator A5069634206 @default.
- W3032830144 creator A5080632105 @default.
- W3032830144 creator A5091238648 @default.
- W3032830144 date "2006-05-25" @default.
- W3032830144 modified "2023-09-25" @default.
- W3032830144 title "Expression of interleukin 1-α, β and interferon-γ in macrophages from endometrium of women with endometriosis" @default.
- W3032830144 doi "https://doi.org/10.3760/j.issn:0529-567x.2006.05.003" @default.
- W3032830144 hasPublicationYear "2006" @default.
- W3032830144 type Work @default.
- W3032830144 sameAs 3032830144 @default.
- W3032830144 citedByCount "0" @default.
- W3032830144 crossrefType "journal-article" @default.
- W3032830144 hasAuthorship W3032830144A5008518733 @default.
- W3032830144 hasAuthorship W3032830144A5034068134 @default.
- W3032830144 hasAuthorship W3032830144A5064701888 @default.
- W3032830144 hasAuthorship W3032830144A5069634206 @default.
- W3032830144 hasAuthorship W3032830144A5080632105 @default.
- W3032830144 hasAuthorship W3032830144A5091238648 @default.
- W3032830144 hasConcept C126322002 @default.
- W3032830144 hasConcept C203014093 @default.
- W3032830144 hasConcept C2776178377 @default.
- W3032830144 hasConcept C2778690821 @default.
- W3032830144 hasConcept C2779522080 @default.
- W3032830144 hasConcept C2779742232 @default.
- W3032830144 hasConcept C2780841837 @default.
- W3032830144 hasConcept C3020380090 @default.
- W3032830144 hasConcept C71924100 @default.
- W3032830144 hasConcept C74172505 @default.
- W3032830144 hasConcept C98119934 @default.
- W3032830144 hasConceptScore W3032830144C126322002 @default.
- W3032830144 hasConceptScore W3032830144C203014093 @default.
- W3032830144 hasConceptScore W3032830144C2776178377 @default.
- W3032830144 hasConceptScore W3032830144C2778690821 @default.
- W3032830144 hasConceptScore W3032830144C2779522080 @default.
- W3032830144 hasConceptScore W3032830144C2779742232 @default.
- W3032830144 hasConceptScore W3032830144C2780841837 @default.
- W3032830144 hasConceptScore W3032830144C3020380090 @default.
- W3032830144 hasConceptScore W3032830144C71924100 @default.
- W3032830144 hasConceptScore W3032830144C74172505 @default.
- W3032830144 hasConceptScore W3032830144C98119934 @default.
- W3032830144 hasIssue "05" @default.
- W3032830144 hasLocation W30328301441 @default.
- W3032830144 hasOpenAccess W3032830144 @default.
- W3032830144 hasPrimaryLocation W30328301441 @default.
- W3032830144 hasRelatedWork W1992425940 @default.
- W3032830144 hasRelatedWork W2021782663 @default.
- W3032830144 hasRelatedWork W2027672877 @default.
- W3032830144 hasRelatedWork W2070715274 @default.
- W3032830144 hasRelatedWork W2129315789 @default.
- W3032830144 hasRelatedWork W2350559289 @default.
- W3032830144 hasRelatedWork W2440302987 @default.
- W3032830144 hasRelatedWork W2570860581 @default.
- W3032830144 hasRelatedWork W2621591249 @default.
- W3032830144 hasRelatedWork W3028812746 @default.
- W3032830144 hasRelatedWork W3029399965 @default.
- W3032830144 hasRelatedWork W3029466992 @default.
- W3032830144 hasRelatedWork W3030828766 @default.
- W3032830144 hasRelatedWork W3030908344 @default.
- W3032830144 hasRelatedWork W3031980376 @default.
- W3032830144 hasRelatedWork W3029321040 @default.
- W3032830144 hasRelatedWork W3029931203 @default.
- W3032830144 hasRelatedWork W3030582357 @default.
- W3032830144 hasRelatedWork W3030952800 @default.
- W3032830144 hasRelatedWork W3032493246 @default.
- W3032830144 hasVolume "41" @default.
- W3032830144 isParatext "false" @default.
- W3032830144 isRetracted "false" @default.
- W3032830144 magId "3032830144" @default.
- W3032830144 workType "article" @default.