Matches in SemOpenAlex for { <https://semopenalex.org/work/W3032852783> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W3032852783 endingPage "1513" @default.
- W3032852783 startingPage "1511" @default.
- W3032852783 abstract "In recent years epidermal growth factor receptor (EGFR) inhibitor is atreatment a major treatment of non-small cell lung cancer (NSCLC).But with the widespread clinical application of resistance as a new difficulty.Now researchers have discovered the main resistance mechanisms is C-MET oncogene amplification.C-MET is a proto oncogene,a protein product of hepatocyte growth factor/scatter factor (HGF/SF) receptor with tyrosine activity.The amplification of C-MET can activated Erb3-PI3K signaling pathway which result in NSCLC resistant to the EGFR-TKI.The patients who resist to EGFR-TKI for about 20％ were due to the amplification of C MET gene.Key words: C-MET; Tyrosine Kinase Inhibitors; Non-small cell lung cancer; Epidermal growth factor receptor ; Resistance ; Hepatocyte growth factor" @default.
- W3032852783 created "2020-06-05" @default.
- W3032852783 creator A5001642071 @default.
- W3032852783 creator A5067152089 @default.
- W3032852783 creator A5069432515 @default.
- W3032852783 date "2012-10-05" @default.
- W3032852783 modified "2023-09-23" @default.
- W3032852783 title "C-MET in non-small-cell lung cancer with acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors" @default.
- W3032852783 doi "https://doi.org/10.3760/cma.j.issn.1673-436x.2012.019.017" @default.
- W3032852783 hasPublicationYear "2012" @default.
- W3032852783 type Work @default.
- W3032852783 sameAs 3032852783 @default.
- W3032852783 citedByCount "0" @default.
- W3032852783 crossrefType "journal-article" @default.
- W3032852783 hasAuthorship W3032852783A5001642071 @default.
- W3032852783 hasAuthorship W3032852783A5067152089 @default.
- W3032852783 hasAuthorship W3032852783A5069432515 @default.
- W3032852783 hasConcept C101544691 @default.
- W3032852783 hasConcept C121608353 @default.
- W3032852783 hasConcept C126322002 @default.
- W3032852783 hasConcept C130287650 @default.
- W3032852783 hasConcept C170493617 @default.
- W3032852783 hasConcept C26375932 @default.
- W3032852783 hasConcept C2776256026 @default.
- W3032852783 hasConcept C2776362946 @default.
- W3032852783 hasConcept C2776996007 @default.
- W3032852783 hasConcept C2779438470 @default.
- W3032852783 hasConcept C2780467284 @default.
- W3032852783 hasConcept C2910739307 @default.
- W3032852783 hasConcept C42362537 @default.
- W3032852783 hasConcept C502942594 @default.
- W3032852783 hasConcept C71924100 @default.
- W3032852783 hasConceptScore W3032852783C101544691 @default.
- W3032852783 hasConceptScore W3032852783C121608353 @default.
- W3032852783 hasConceptScore W3032852783C126322002 @default.
- W3032852783 hasConceptScore W3032852783C130287650 @default.
- W3032852783 hasConceptScore W3032852783C170493617 @default.
- W3032852783 hasConceptScore W3032852783C26375932 @default.
- W3032852783 hasConceptScore W3032852783C2776256026 @default.
- W3032852783 hasConceptScore W3032852783C2776362946 @default.
- W3032852783 hasConceptScore W3032852783C2776996007 @default.
- W3032852783 hasConceptScore W3032852783C2779438470 @default.
- W3032852783 hasConceptScore W3032852783C2780467284 @default.
- W3032852783 hasConceptScore W3032852783C2910739307 @default.
- W3032852783 hasConceptScore W3032852783C42362537 @default.
- W3032852783 hasConceptScore W3032852783C502942594 @default.
- W3032852783 hasConceptScore W3032852783C71924100 @default.
- W3032852783 hasIssue "19" @default.
- W3032852783 hasLocation W30328527831 @default.
- W3032852783 hasOpenAccess W3032852783 @default.
- W3032852783 hasPrimaryLocation W30328527831 @default.
- W3032852783 hasRelatedWork W1968184782 @default.
- W3032852783 hasRelatedWork W1977992762 @default.
- W3032852783 hasRelatedWork W2050459629 @default.
- W3032852783 hasRelatedWork W2141923913 @default.
- W3032852783 hasRelatedWork W2145580674 @default.
- W3032852783 hasRelatedWork W2181812152 @default.
- W3032852783 hasRelatedWork W2342364781 @default.
- W3032852783 hasRelatedWork W2351942773 @default.
- W3032852783 hasRelatedWork W2566559875 @default.
- W3032852783 hasRelatedWork W2698318545 @default.
- W3032852783 hasRelatedWork W2717400244 @default.
- W3032852783 hasRelatedWork W2756128561 @default.
- W3032852783 hasRelatedWork W2798012260 @default.
- W3032852783 hasRelatedWork W2889673133 @default.
- W3032852783 hasRelatedWork W2894646759 @default.
- W3032852783 hasRelatedWork W2901365094 @default.
- W3032852783 hasRelatedWork W3032385392 @default.
- W3032852783 hasRelatedWork W3032800087 @default.
- W3032852783 hasRelatedWork W3044006916 @default.
- W3032852783 hasRelatedWork W3113067628 @default.
- W3032852783 hasVolume "32" @default.
- W3032852783 isParatext "false" @default.
- W3032852783 isRetracted "false" @default.
- W3032852783 magId "3032852783" @default.
- W3032852783 workType "article" @default.