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- W3032956371 abstract "We sought to investigate erectile function (EF) outcomes after Holmium Laser Enucleation of the Prostate (HoLEP) in patients consecutively treated at a single center. The ExpHo trial (NCT03583034) is a prospective observational study collecting data of patients submitted to HoLEP at a single academic center. Before surgery, all patients completed the International Index of Erectile Function (IIEF) and the International Prostatic Symptoms Score. Non-sexually active patients before surgery were excluded. Patients were re-assessed at 1 week, 1 month, and 3 months after HoLEP. Postoperative EF recovery was defined as an IIEF-EF score equal or higher to baseline values. Kaplan-Meier analyses were used to estimate the probability of EF recovery over time. Cox-regression analysis tested predictors of EF recovery. Data were available for 72 patients. Median (IQR) age was 66 (62,73) years. Median (IQR) baseline IPSS score was 20(14, 23.5) and prostate volume (PV) 90 cc (65, 115). We observed a significant decrease of mean IIEF-EF score at 1-mo follow-up compared to baseline (18.8 vs. 13.5; p=0.0008) with a subsequent improvement at 3-mo assessment (IIEF-EF: 17.1). The estimated probability of EF recovery after surgery was 12% and 53% at 1-mo and 3-mo after surgery, respectively. At cox regression analysis, preoperative (i.e., age, BMI, CCI, PV, IIEF, IPSS) and intraoperative variables (i.e., duration of surgery, total energy delivered, intraoperative complications) were not associated with the probability of EF recovery. Conversely, patients reporting a decrease of sexual desire (HR 0.22; 95%CI: 0.5, 0.9) and overall sexual satisfaction scores (HR: 0.20; 95%CI 0.1,0.6) were less likely to recover EF baseline level." @default.
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- W3032956371 date "2020-06-01" @default.
- W3032956371 modified "2023-10-01" @default.
- W3032956371 title "P-02-45 Time-to-Recovery of Baseline Erectile Function after HoLEP - Results From a Prospective Trial (EXPHO)" @default.
- W3032956371 doi "https://doi.org/10.1016/j.jsxm.2020.04.199" @default.
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