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• W3033127934 abstract "A metabolome is a set of small molecules in the body: peptides, lipids, amino acids, nucleic acids, carbohydrates, biogenic amines, vitamins, minerals, as well as any chemical compounds that a person comes into contact with, including nutritional supplements, medicines, cosmetics, toxins. Metabolomics is a study of all the metabolites present in the biological system. This science has become a reality due to the development of two modern technological platforms: mass spectrometry, the unique mass-charge ratio for each metabolite that identifies thousands of compounds in one sample, and nuclear magnetic resonance spectroscopy, which makes it possible to determine metabolites in spectral arrays by shifting their signal relative to reference signal. The concepts of metabolomics and metabolome are given in the review, the methods of research and data interpretation are presented, the main applications of metabolomics in the field of diagnosis of central nervous system diseases. The search for prognostic markers and new therapeutic targets, the metabolic composition of cerebrospinal fluid in the normal state and its changes in pathology are described." @default.
• W3033127934 created "2020-06-12" @default.
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• W3033127934 date "2020-04-17" @default.
• W3033127934 modified "2023-09-25" @default.
• W3033127934 title "Metabolome of the Brain" @default.
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• W3033127934 doi "https://doi.org/10.30629/2658-7947-2020-25-1-4-12" @default.
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