Matches in SemOpenAlex for { <https://semopenalex.org/work/W3033127988> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W3033127988 abstract "Abstract Due to their self-regulating behavior, pH-responsive hydrogels are frequently considered in the development of functional biomaterials. A rational approach to designing new biomaterials imposes the need to understate their interaction with protein solutions. On the basis of theoretical work, this chapter describes the adsorption of proteins and peptides to films of cross-linked pH-sensitive polymers. Particular emphasis is placed on the physical chemistry that emerges from the charge regulation properties of hydrogels and proteins. As a result of spatial confinement, the acidic units that compose a polymer network modify their protonation state as well as the composition of the surroundings; the local pH drops inside the hydrogel, increasing protein protonation upon adsorption. Having different amino acid residues that protonate or deprotonate under different conditions supplies proteins with degrees of freedom to modify their net charge and, thus, modulate the electrostatic interactions with a given hydrogel that drive adsorption. Tailoring a polymer network’s chemical composition allows for the separation and localization of specific components from multiprotein solutions using pH." @default.
- W3033127988 created "2020-06-12" @default.
- W3033127988 creator A5039929884 @default.
- W3033127988 date "2020-01-01" @default.
- W3033127988 modified "2023-10-07" @default.
- W3033127988 title "An example of theoretical approaches in polymer hydrogels: insights into the behavior of pH-responsive nanofilms" @default.
- W3033127988 doi "https://doi.org/10.1016/b978-0-12-816808-0.00007-x" @default.
- W3033127988 hasPublicationYear "2020" @default.
- W3033127988 type Work @default.
- W3033127988 sameAs 3033127988 @default.
- W3033127988 citedByCount "0" @default.
- W3033127988 crossrefType "book-chapter" @default.
- W3033127988 hasAuthorship W3033127988A5039929884 @default.
- W3033127988 hasConcept C108586683 @default.
- W3033127988 hasConcept C127413603 @default.
- W3033127988 hasConcept C145148216 @default.
- W3033127988 hasConcept C150394285 @default.
- W3033127988 hasConcept C153356533 @default.
- W3033127988 hasConcept C159467904 @default.
- W3033127988 hasConcept C171250308 @default.
- W3033127988 hasConcept C178790620 @default.
- W3033127988 hasConcept C185592680 @default.
- W3033127988 hasConcept C188027245 @default.
- W3033127988 hasConcept C192562407 @default.
- W3033127988 hasConcept C2992123155 @default.
- W3033127988 hasConcept C30095370 @default.
- W3033127988 hasConcept C42360764 @default.
- W3033127988 hasConcept C521977710 @default.
- W3033127988 hasConcept C53105671 @default.
- W3033127988 hasConcept C88001094 @default.
- W3033127988 hasConceptScore W3033127988C108586683 @default.
- W3033127988 hasConceptScore W3033127988C127413603 @default.
- W3033127988 hasConceptScore W3033127988C145148216 @default.
- W3033127988 hasConceptScore W3033127988C150394285 @default.
- W3033127988 hasConceptScore W3033127988C153356533 @default.
- W3033127988 hasConceptScore W3033127988C159467904 @default.
- W3033127988 hasConceptScore W3033127988C171250308 @default.
- W3033127988 hasConceptScore W3033127988C178790620 @default.
- W3033127988 hasConceptScore W3033127988C185592680 @default.
- W3033127988 hasConceptScore W3033127988C188027245 @default.
- W3033127988 hasConceptScore W3033127988C192562407 @default.
- W3033127988 hasConceptScore W3033127988C2992123155 @default.
- W3033127988 hasConceptScore W3033127988C30095370 @default.
- W3033127988 hasConceptScore W3033127988C42360764 @default.
- W3033127988 hasConceptScore W3033127988C521977710 @default.
- W3033127988 hasConceptScore W3033127988C53105671 @default.
- W3033127988 hasConceptScore W3033127988C88001094 @default.
- W3033127988 hasLocation W30331279881 @default.
- W3033127988 hasOpenAccess W3033127988 @default.
- W3033127988 hasPrimaryLocation W30331279881 @default.
- W3033127988 hasRelatedWork W14717642 @default.
- W3033127988 hasRelatedWork W21763203 @default.
- W3033127988 hasRelatedWork W2217355 @default.
- W3033127988 hasRelatedWork W22454291 @default.
- W3033127988 hasRelatedWork W23533103 @default.
- W3033127988 hasRelatedWork W24237016 @default.
- W3033127988 hasRelatedWork W25114219 @default.
- W3033127988 hasRelatedWork W34775196 @default.
- W3033127988 hasRelatedWork W9615907 @default.
- W3033127988 hasRelatedWork W9674113 @default.
- W3033127988 isParatext "false" @default.
- W3033127988 isRetracted "false" @default.
- W3033127988 magId "3033127988" @default.
- W3033127988 workType "book-chapter" @default.