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- W3033132969 abstract "Background: There is conflicting data regarding the association between low levels of plasma vitamin D and ischemic heart disease (IHD). We aimed to investigate the relationship between plasma vitamin D levels and heart valve calcification in hospitalized patients with IHD versus non-IHD controls. Methods: A prospective case control study comprising two age and gender-matched groups. The study group included consecutive patients hospitalized due to acute coronary syndrome (ACS); the control group included consecutive non- IHD patients hospitalized for non-cardiac causes. Blood samples for 25-hydroxyvitamin D level (25(OH)D) were drawn. An echocardiogram was performed during the first 3 days of hospitalization and reviewed for presence and degree of valvular calcification (VC). Results: Forty patients with ACS and 40 controls (age 58 ± 11 years, 64% male in both groups) were included. Mean plasma 25(OH)D vitamin level in the entire cohort was 24.5 ± 8 ng/ml. Valve calcification rates were similar in ACS versus non-ACS group (28 vs. 21 had VC; 18 vs. 12 had aortic valve calcification (AVC); 21 vs. 14 had mitral valve calcification (MVC), respectively; p=NS for all). We found no significant relationship between vitamin D level and VC, AVC, or MVC rate or degree in the entire cohort and in each group alone (p=NS for all). There was a negative correlation between 25(OH)D levels and age in the ACS group (r=-0.399, p=0.012). Conclusions: We did not find a significant relationship between plasma vitamin D levels and the rate or degree of calcification of either aortic/mitral/both valves in hospitalized patients with/without IHD." @default.
- W3033132969 created "2020-06-12" @default.
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- W3033132969 date "2020-01-01" @default.
- W3033132969 modified "2023-09-27" @default.
- W3033132969 title "The Relationship between Plasma Vitamin D Level and Heart Valves Calcification" @default.
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- W3033132969 doi "https://doi.org/10.37421/jcdd.2020.8.406" @default.
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