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• W3033156776 endingPage "103657" @default.
• W3033156776 startingPage "103657" @default.
• W3033156776 abstract "Theoretical frameworks propose that threat-related attention, which is typically assessed using the dot-probe paradigm, plays a key role in social anxiety. Within the dot-probe paradigm, novel computational approaches demonstrate that anxious individuals exhibit multiple patterns of threat-related attention on separate trials. However, no research has leveraged such novel computational methods to delineate the neural substrates of threat-related attention patterns in social anxiety. To address this issue, fifty-three socially anxious adults (22.38 ± 3.12, 33 females) completed an fMRI-based dot-probe paradigm. A novel, response-based computation approach revealed conjoint patterns of vigilant orientation, avoidant orientation, slow disengagement, and fast disengagement, which were masked by standard computation measures. Compared to vigilant orientation and fast disengagement, avoidant orientation and slow disengagement were greater in magnitude, respectively. Mirroring behavioral findings, avoidant orientation and slow disengagement elicited greater deactivation of several regions within the Default Mode Network and stronger connectivity between the right amygdala and superior temporal sulcus. Taken together, these results suggest that distinct neural processes facilitate the heterogeneous expression of threat-related attention in social anxiety." @default.
• W3033156776 created "2020-06-12" @default.
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• W3033156776 date "2020-09-01" @default.
• W3033156776 modified "2023-10-04" @default.
• W3033156776 title "Neural mechanisms underlying heterogeneous expression of threat-related attention in social anxiety" @default.
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• W3033156776 doi "https://doi.org/10.1016/j.brat.2020.103657" @default.
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