Matches in SemOpenAlex for { <https://semopenalex.org/work/W3033234082> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W3033234082 endingPage "313" @default.
- W3033234082 startingPage "306" @default.
- W3033234082 abstract "Introduction and objective Pseudomonas aeruginosa is an opportunistic pathogen that causes difficult with treating infections, especially in the immunocompromised and patients with some underlying disease. The aim of the study is to assess the antibiotic resistance, biofilm formation, and the presence of genes encoding various virulence factors in clinical isolates of P. aeruginosa. Material and methods Seventy-three clinical isolates of Pseudomonas aeruginosa were tested. Antimicrobial Susceptibility Testing (AST) and carbapenemases production was performed in accordance with the EUCAST guidelines. The ability to form biofilm was assessed by crystal violet assay. Genes encoding selected virulence factors were detected using standard polymerase chain reaction (PCR). Results Among the 73 clinical isolates of P. aeruginosa, 41.1% were resistant to imipenem, 61.6% to meropenem, 30.1% to ciprofloxacin and 15.1% to tobramycin. Over 20% of isolates were producers of MBL. Antibiotic resistance profiling revealed that 23.3% of strains were sensitive to all antibiotics, 60.3% were LDR phenotype, and 16.4% were MDR phenotype. The majority of strains (73.6%) were strong-biofilm producers, 17.0% were moderate and 9.4% were weak biofilm producers. PCR analysis showed the presence of lasB, aprE and prpL genes in most of the tested strains (93.1%, 87.7% and 74.0%, respectively). Among strong biofilm producers, 22.2% were MDR, 63.0% of strains represented LDR phenotype, and 14.8% were sensitive to all antibiotics. Moderate and weak biofilm producers were LDR and sensitive phenotypes only (respectively, 58.3% and 42.9 - LDR, 41.7 and 51.7% - sensitive). Conclusions High frequency of MDR strains and their ability of biofilm formation and virulence factors may be a threat to effective therapy, and can increase morbidity and mortality of infected patients." @default.
- W3033234082 created "2020-06-12" @default.
- W3033234082 creator A5000710425 @default.
- W3033234082 creator A5000941484 @default.
- W3033234082 creator A5011747830 @default.
- W3033234082 creator A5064749301 @default.
- W3033234082 creator A5090420292 @default.
- W3033234082 date "2021-06-14" @default.
- W3033234082 modified "2023-10-18" @default.
- W3033234082 title "Relationship between antibiotic resistance, biofilm formation, genes coding virulence factors and source of origin of <i>Pseudomonas aeruginosa</i> clinical strains" @default.
- W3033234082 doi "https://doi.org/10.26444/aaem/122682" @default.
- W3033234082 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34184515" @default.
- W3033234082 hasPublicationYear "2021" @default.
- W3033234082 type Work @default.
- W3033234082 sameAs 3033234082 @default.
- W3033234082 citedByCount "14" @default.
- W3033234082 countsByYear W30332340822021 @default.
- W3033234082 countsByYear W30332340822022 @default.
- W3033234082 countsByYear W30332340822023 @default.
- W3033234082 crossrefType "journal-article" @default.
- W3033234082 hasAuthorship W3033234082A5000710425 @default.
- W3033234082 hasAuthorship W3033234082A5000941484 @default.
- W3033234082 hasAuthorship W3033234082A5011747830 @default.
- W3033234082 hasAuthorship W3033234082A5064749301 @default.
- W3033234082 hasAuthorship W3033234082A5090420292 @default.
- W3033234082 hasBestOaLocation W30332340821 @default.
- W3033234082 hasConcept C104317684 @default.
- W3033234082 hasConcept C2777637488 @default.
- W3033234082 hasConcept C501593827 @default.
- W3033234082 hasConcept C523546767 @default.
- W3033234082 hasConcept C54355233 @default.
- W3033234082 hasConcept C58123911 @default.
- W3033234082 hasConcept C60987743 @default.
- W3033234082 hasConcept C86803240 @default.
- W3033234082 hasConcept C89423630 @default.
- W3033234082 hasConcept C94665300 @default.
- W3033234082 hasConceptScore W3033234082C104317684 @default.
- W3033234082 hasConceptScore W3033234082C2777637488 @default.
- W3033234082 hasConceptScore W3033234082C501593827 @default.
- W3033234082 hasConceptScore W3033234082C523546767 @default.
- W3033234082 hasConceptScore W3033234082C54355233 @default.
- W3033234082 hasConceptScore W3033234082C58123911 @default.
- W3033234082 hasConceptScore W3033234082C60987743 @default.
- W3033234082 hasConceptScore W3033234082C86803240 @default.
- W3033234082 hasConceptScore W3033234082C89423630 @default.
- W3033234082 hasConceptScore W3033234082C94665300 @default.
- W3033234082 hasIssue "2" @default.
- W3033234082 hasLocation W30332340821 @default.
- W3033234082 hasOpenAccess W3033234082 @default.
- W3033234082 hasPrimaryLocation W30332340821 @default.
- W3033234082 hasRelatedWork W1968602861 @default.
- W3033234082 hasRelatedWork W1974885234 @default.
- W3033234082 hasRelatedWork W2039953997 @default.
- W3033234082 hasRelatedWork W2129197708 @default.
- W3033234082 hasRelatedWork W2277991016 @default.
- W3033234082 hasRelatedWork W2590948392 @default.
- W3033234082 hasRelatedWork W2790286024 @default.
- W3033234082 hasRelatedWork W2903615114 @default.
- W3033234082 hasRelatedWork W3139452833 @default.
- W3033234082 hasRelatedWork W3210876037 @default.
- W3033234082 hasVolume "28" @default.
- W3033234082 isParatext "false" @default.
- W3033234082 isRetracted "false" @default.
- W3033234082 magId "3033234082" @default.
- W3033234082 workType "article" @default.