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- W3033252302 endingPage "5653" @default.
- W3033252302 startingPage "5639" @default.
- W3033252302 abstract "The parietal cortex (PC) is implicated in a confusing myriad of different cognitive processes/tasks. Consequently, understanding the nature and organization of the core underlying neurocomputations is challenging. According to the Parietal Unified Connectivity-biased Computation model, two properties underpin PC function and organization. Firstly, PC is a multidomain, context-dependent buffer of time- and space-varying input, the function of which, over time, becomes sensitive to the statistical temporal/spatial structure of events. Secondly, over and above this core buffering computation, differences in long-range connectivity will generate graded variations in task engagement across subregions. The current study tested these hypotheses using a group independent component analysis technique with two independent functional magnetic resonance imaging datasets (task and resting state data). Three functional organizational principles were revealed: Factor 1, inferior PC was sensitive to the statistical structure of sequences for all stimulus types (pictures, sentences, numbers); Factor 2, a dorsal-ventral variation in generally task-positive versus task-negative (variable) engagement; and Factor 3, an anterior-posterior dimension in inferior PC reflecting different engagement in verbal versus visual tasks, respectively. Together, the data suggest that the core neurocomputation implemented by PC is common across domains, with graded task engagement across regions reflecting variations in the connectivity of task-specific networks that interact with PC." @default.
- W3033252302 created "2020-06-12" @default.
- W3033252302 creator A5015502189 @default.
- W3033252302 creator A5021432172 @default.
- W3033252302 creator A5055451526 @default.
- W3033252302 date "2020-06-09" @default.
- W3033252302 modified "2023-10-16" @default.
- W3033252302 title "Overarching Principles and Dimensions of the Functional Organization in the Inferior Parietal Cortex" @default.
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- W3033252302 doi "https://doi.org/10.1093/cercor/bhaa133" @default.
- W3033252302 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7116231" @default.
- W3033252302 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32515783" @default.
- W3033252302 hasPublicationYear "2020" @default.