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- W3033329026 endingPage "2885" @default.
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- W3033329026 abstract "Background Total knee arthroplasty (TKA) demand continues to rise, but we are also gaining greater insight into patient risk factors for postoperative complications and excess resource utilization. There has been growing interest in frailty and malnutrition as risk factors, although they are often mistakenly used interchangeably. We aimed at identifying the incidence of their coexistence, and the magnitude of risk they confer to TKA patients. Methods We queried the American College of Surgeons-National Surgery Quality Improvement Program database to identify 4 patient cohorts: healthy/normal serum albumin, healthy/hypoalbuminemic patients, normoalbuminemic/medically frail patients (defined by modified frailty index), and hypoalbuminemic/frail patients. We performed both univariate and multivariate analyses to quantify the risk conferred by each condition in isolation, and in coexistence. Results Of 179,702 elective TKA cases from 2006 to 2018, 18.6% of patients were frail only, 3.0% were hypoalbuminemic -only, and just 1.2% were both frail and hypoalbuminemic. The raw rate of any complication was highest in frail/hypoalbuminemic patients (8.7%), 5.2% in hypoalbuminemic patients, 4.8% in frail patients, and just 3.4% in healthy patients (P < .001); the multivariate model revealed odds ratio of a complication in frail/hypoalbuminemic group of 2.40 (95% confidence interval = 1.27-1.63; P < .001). Mortality within 30 days was highest in the frail/hypoalbuminemic cohort (1.0%), and just 0.1% in healthy patients, and the multivariate model noted an odds ratio of 9.43 for these patients (95% confidence interval = 5.92-14.93; P < .001). The odds of all studied complications were highest in the frail/hypoalbuminemic group. Conclusion Frailty and hypoalbuminemia represent distinct conditions and are independent risk factors for a complication after TKA. Their coexistence imparts a synergistic association with the risk of post-TKA complications." @default.
- W3033329026 created "2020-06-12" @default.
- W3033329026 creator A5022554332 @default.
- W3033329026 creator A5034873207 @default.
- W3033329026 creator A5043424535 @default.
- W3033329026 creator A5063843782 @default.
- W3033329026 creator A5074587850 @default.
- W3033329026 date "2020-10-01" @default.
- W3033329026 modified "2023-10-13" @default.
- W3033329026 title "Concomitant Malnutrition and Frailty Are Uncommon, but Significant Risk Factors for Mortality and Complication Following Primary Total Knee Arthroplasty" @default.
- W3033329026 cites W1222543884 @default.
- W3033329026 cites W1488582831 @default.
- W3033329026 cites W1492830089 @default.
- W3033329026 cites W1571896605 @default.
- W3033329026 cites W1826597520 @default.
- W3033329026 cites W1843513215 @default.
- W3033329026 cites W1910193113 @default.
- W3033329026 cites W1970920313 @default.
- W3033329026 cites W1995762183 @default.
- W3033329026 cites W2000430496 @default.
- W3033329026 cites W2005403243 @default.
- W3033329026 cites W2006269444 @default.
- W3033329026 cites W2007904558 @default.
- W3033329026 cites W2011324066 @default.
- W3033329026 cites W2020273589 @default.
- W3033329026 cites W2029186176 @default.
- W3033329026 cites W2053460039 @default.
- W3033329026 cites W2065853397 @default.
- W3033329026 cites W2080897463 @default.
- W3033329026 cites W2083812983 @default.
- W3033329026 cites W2086958266 @default.
- W3033329026 cites W2087111646 @default.
- W3033329026 cites W2096671308 @default.
- W3033329026 cites W2101523679 @default.
- W3033329026 cites W2115655573 @default.
- W3033329026 cites W2122860550 @default.
- W3033329026 cites W2132008998 @default.
- W3033329026 cites W2174612525 @default.
- W3033329026 cites W2200548371 @default.
- W3033329026 cites W2305474098 @default.
- W3033329026 cites W2313168015 @default.
- W3033329026 cites W2319973928 @default.
- W3033329026 cites W2344736486 @default.
- W3033329026 cites W2346048677 @default.
- W3033329026 cites W2417530847 @default.
- W3033329026 cites W2420495406 @default.
- W3033329026 cites W2464496956 @default.
- W3033329026 cites W2516133264 @default.
- W3033329026 cites W2521854653 @default.
- W3033329026 cites W2545921644 @default.
- W3033329026 cites W2552219167 @default.
- W3033329026 cites W2566317595 @default.
- W3033329026 cites W2567368528 @default.
- W3033329026 cites W2587028269 @default.
- W3033329026 cites W2592916149 @default.
- W3033329026 cites W2596164391 @default.
- W3033329026 cites W2597974650 @default.
- W3033329026 cites W2624181407 @default.
- W3033329026 cites W2734936992 @default.
- W3033329026 cites W2739390594 @default.
- W3033329026 cites W2747544320 @default.
- W3033329026 cites W2752956767 @default.
- W3033329026 cites W2753849044 @default.
- W3033329026 cites W2768407667 @default.
- W3033329026 cites W2778346319 @default.
- W3033329026 cites W2789965421 @default.
- W3033329026 cites W2790371620 @default.
- W3033329026 cites W2792853408 @default.
- W3033329026 cites W2794315496 @default.
- W3033329026 cites W2795351273 @default.
- W3033329026 cites W2800666727 @default.
- W3033329026 cites W2800842784 @default.
- W3033329026 cites W2802986244 @default.
- W3033329026 cites W2808229812 @default.
- W3033329026 cites W2808943546 @default.
- W3033329026 cites W2811478901 @default.
- W3033329026 cites W2890318547 @default.
- W3033329026 cites W2893567244 @default.
- W3033329026 cites W2893845733 @default.
- W3033329026 cites W2896586673 @default.
- W3033329026 cites W2907656398 @default.
- W3033329026 cites W2909551888 @default.
- W3033329026 cites W2910984622 @default.
- W3033329026 cites W2912977329 @default.
- W3033329026 cites W2913013873 @default.
- W3033329026 cites W2914710168 @default.
- W3033329026 cites W2921736965 @default.
- W3033329026 cites W2922282717 @default.
- W3033329026 cites W2928356089 @default.
- W3033329026 cites W2943022784 @default.
- W3033329026 cites W2957196075 @default.
- W3033329026 cites W2968450926 @default.
- W3033329026 cites W2971397225 @default.
- W3033329026 cites W2996674410 @default.
- W3033329026 cites W3025248755 @default.
- W3033329026 cites W4231899502 @default.
- W3033329026 doi "https://doi.org/10.1016/j.arth.2020.05.062" @default.
- W3033329026 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32576431" @default.