FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3033459488> ?p ?o ?g. }

• W3033459488 endingPage "C249" @default.
• W3033459488 startingPage "C244" @default.
• W3033459488 abstract "The outbreak of COVID-19 pneumonia caused by a new coronavirus (severe acute respiratory syndrome coronavirus 2, SARS-CoV-2) is posing a global health emergency and has led to more than 380,000 deaths worldwide. The cell entry of SARS-CoV-2 depends on two host proteins angiotensin-converting enzyme 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2). There is currently no vaccine available and also no effective drug for the treatment of COVID-19. Hydrogen sulfide (H 2 S) as a novel gasotransmitter has been shown to protect against lung damage via its anti-inflammation, antioxidative stress, antiviral, prosurvival, and antiaging effects. In light of the research advances on H 2 S signaling in biology and medicine, this review proposed H 2 S as a potential defense against COVID-19. It is suggested that H 2 S may block SARS-CoV-2 entry into host cells by interfering with ACE2 and TMPRSS2, inhibit SARS-CoV-2 replication by attenuating virus assembly/release, and protect SARS-CoV-2-induced lung damage by suppressing immune response and inflammation development. Preclinical studies and clinical trials with slow-releasing H 2 S donor(s) or the activators of endogenous H 2 S-generating enzymes should be considered as a preventative treatment or therapy for COVID-19." @default.
• W3033459488 created "2020-06-12" @default.
• W3033459488 creator A5007660396 @default.
• W3033459488 date "2020-08-01" @default.
• W3033459488 modified "2023-10-18" @default.
• W3033459488 title "H₂S as a potential defense against COVID-19?" @default.
• W3033459488 cites W1491524802 @default.
• W3033459488 cites W1595363731 @default.
• W3033459488 cites W1964155163 @default.
• W3033459488 cites W1964982019 @default.
• W3033459488 cites W2006242918 @default.
• W3033459488 cites W2008076845 @default.
• W3033459488 cites W2008216891 @default.
• W3033459488 cites W2024264629 @default.
• W3033459488 cites W2030669250 @default.
• W3033459488 cites W2056828828 @default.
• W3033459488 cites W2059874105 @default.
• W3033459488 cites W2073876100 @default.
• W3033459488 cites W2082981201 @default.
• W3033459488 cites W2088894435 @default.
• W3033459488 cites W2139507856 @default.
• W3033459488 cites W2161477365 @default.
• W3033459488 cites W2164206394 @default.
• W3033459488 cites W2164611317 @default.
• W3033459488 cites W2167617896 @default.
• W3033459488 cites W2171671715 @default.
• W3033459488 cites W2225716131 @default.
• W3033459488 cites W2226662974 @default.
• W3033459488 cites W2310142209 @default.
• W3033459488 cites W2360520526 @default.
• W3033459488 cites W2444128733 @default.
• W3033459488 cites W2462958992 @default.
• W3033459488 cites W2520977577 @default.
• W3033459488 cites W2567255471 @default.
• W3033459488 cites W2567378564 @default.
• W3033459488 cites W2571716788 @default.
• W3033459488 cites W2592999011 @default.
• W3033459488 cites W2613446160 @default.
• W3033459488 cites W2740908832 @default.
• W3033459488 cites W2756864383 @default.
• W3033459488 cites W2762846413 @default.
• W3033459488 cites W2765416660 @default.
• W3033459488 cites W2766539883 @default.
• W3033459488 cites W2774207546 @default.
• W3033459488 cites W2786677683 @default.
• W3033459488 cites W2799767529 @default.
• W3033459488 cites W2801224719 @default.
• W3033459488 cites W2801727308 @default.
• W3033459488 cites W2803997671 @default.
• W3033459488 cites W2884522517 @default.
• W3033459488 cites W2892963379 @default.
• W3033459488 cites W2900341519 @default.
• W3033459488 cites W2901704400 @default.
• W3033459488 cites W2907527513 @default.
• W3033459488 cites W2937169220 @default.
• W3033459488 cites W2988309021 @default.
• W3033459488 cites W2990839503 @default.
• W3033459488 cites W3003464757 @default.
• W3033459488 cites W3004280078 @default.
• W3033459488 cites W3005655936 @default.
• W3033459488 cites W3007986422 @default.
• W3033459488 cites W3008443627 @default.
• W3033459488 cites W3009335299 @default.
• W3033459488 cites W3009912996 @default.
• W3033459488 cites W3010441732 @default.
• W3033459488 cites W3012180666 @default.
• W3033459488 cites W3012519689 @default.
• W3033459488 cites W3012725239 @default.
• W3033459488 cites W3012818885 @default.
• W3033459488 cites W3013244923 @default.
• W3033459488 cites W3013694216 @default.
• W3033459488 cites W3014656992 @default.
• W3033459488 cites W3015134137 @default.
• W3033459488 cites W3015438945 @default.
• W3033459488 cites W3017394074 @default.
• W3033459488 cites W3020048093 @default.
• W3033459488 cites W3020251208 @default.
• W3033459488 cites W871290568 @default.
• W3033459488 doi "https://doi.org/10.1152/ajpcell.00187.2020" @default.
• W3033459488 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7381713" @default.
• W3033459488 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32515982" @default.
• W3033459488 hasPublicationYear "2020" @default.
• W3033459488 type Work @default.
• W3033459488 sameAs 3033459488 @default.
• W3033459488 citedByCount "43" @default.
• W3033459488 countsByYear W30334594882020 @default.
• W3033459488 countsByYear W30334594882021 @default.
• W3033459488 countsByYear W30334594882022 @default.
• W3033459488 countsByYear W30334594882023 @default.
• W3033459488 crossrefType "journal-article" @default.
• W3033459488 hasAuthorship W3033459488A5007660396 @default.
• W3033459488 hasBestOaLocation W30334594882 @default.
• W3033459488 hasConcept C126322002 @default.
• W3033459488 hasConcept C159047783 @default.
• W3033459488 hasConcept C203014093 @default.
• W3033459488 hasConcept C2776914184 @default.
• W3033459488 hasConcept C2777648638 @default.
• W3033459488 hasConcept C2777714996 @default.

• next