FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3033460778> ?p ?o ?g. }

• W3033460778 endingPage "2310" @default.
• W3033460778 startingPage "2310" @default.
• W3033460778 abstract "<h3>Importance</h3> Illicit drug use is among the most common causes of preventable morbidity and mortality in the US. <h3>Objective</h3> To systematically review the literature on screening and interventions for drug use to inform the US Preventive Services Task Force. <h3>Data Sources</h3> MEDLINE, PubMed, PsycINFO, Embase, and Cochrane Central Register of Controlled Trials through September 18, 2018; literature surveillance through September 21, 2019. <h3>Study Selection</h3> Test accuracy studies to detect drug misuse and randomized clinical trials of screening and interventions to reduce drug use. <h3>Data Extraction and Synthesis</h3> Critical appraisal and data abstraction by 2 reviewers and random-effects meta-analyses. <h3>Main Outcomes and Measures</h3> Sensitivity, specificity, drug use and other health, social, and legal outcomes. <h3>Results</h3> Ninety-nine studies (N = 84 206) were included. Twenty-eight studies (n = 65 720) addressed drug screening accuracy. Among adults, sensitivity and specificity of screening tools for detecting unhealthy drug use ranged from 0.71 to 0.94 and 0.87 to 0.97, respectively. Interventions to reduce drug use were evaluated in 52 trials (n = 15 659) of psychosocial interventions, 7 trials (n = 1109) of opioid agonist therapy, and 13 trials (n = 1718) of naltrexone. Psychosocial interventions were associated with increased likelihood of drug use abstinence (15 trials, n = 3636; relative risk [RR], 1.60 [95% CI, 1.24 to 2.13]; absolute risk difference [ARD], 9% [95% CI, 5% to 15%]) and reduced number of drug use days (19 trials, n = 5085; mean difference, –0.49 day in the last 7 days [95% CI, –0.85 to –0.13]) vs no psychosocial intervention at 3- to 4-month follow-up. In treatment-seeking populations, opioid agonist therapy and naltrexone were associated with decreased risk of drug use relapse (4 trials, n = 567; RR, 0.75 [95% CI, 0.59 to 0.82]; ARD, –35% [95% CI, –67% to –3%] and 12 trials, n = 1599; RR, 0.73 [95% CI, 0.62 to 0.85]; ARD, –18% [95% CI, –26% to –10%], respectively) vs placebo or no medication. While evidence on harms was limited, it indicated no increased risk of serious adverse events. <h3>Conclusions and Relevance</h3> Several screening instruments with acceptable sensitivity and specificity are available to screen for drug use, although there is no direct evidence on the benefits or harms of screening. Pharmacotherapy and psychosocial interventions are effective at improving drug use outcomes, but evidence of effectiveness remains primarily derived from trials conducted in treatment-seeking populations." @default.
• W3033460778 created "2020-06-12" @default.
• W3033460778 creator A5001137551 @default.
• W3033460778 creator A5026593887 @default.
• W3033460778 creator A5029757864 @default.
• W3033460778 creator A5030818110 @default.
• W3033460778 creator A5032309159 @default.
• W3033460778 creator A5032552265 @default.
• W3033460778 creator A5052253657 @default.
• W3033460778 creator A5068044194 @default.
• W3033460778 creator A5070442023 @default.
• W3033460778 creator A5078294438 @default.
• W3033460778 date "2020-06-09" @default.
• W3033460778 modified "2023-10-15" @default.
• W3033460778 title "Screening for Unhealthy Drug Use" @default.
• W3033460778 cites W1721587613 @default.
• W3033460778 cites W1811656171 @default.
• W3033460778 cites W1829714698 @default.
• W3033460778 cites W1897292339 @default.
• W3033460778 cites W1923275361 @default.
• W3033460778 cites W1936008785 @default.
• W3033460778 cites W1968086599 @default.
• W3033460778 cites W1969954835 @default.
• W3033460778 cites W1971658792 @default.
• W3033460778 cites W1974154449 @default.
• W3033460778 cites W1977988060 @default.
• W3033460778 cites W1979363419 @default.
• W3033460778 cites W1980154695 @default.
• W3033460778 cites W1981127653 @default.
• W3033460778 cites W1981885001 @default.
• W3033460778 cites W1985022086 @default.
• W3033460778 cites W1987279362 @default.
• W3033460778 cites W1989357750 @default.
• W3033460778 cites W1989482753 @default.
• W3033460778 cites W1990366210 @default.
• W3033460778 cites W1990854956 @default.
• W3033460778 cites W1996661711 @default.
• W3033460778 cites W2004788852 @default.
• W3033460778 cites W2010468128 @default.
• W3033460778 cites W2014689998 @default.
• W3033460778 cites W2017872800 @default.
• W3033460778 cites W2022063518 @default.
• W3033460778 cites W2022195719 @default.
• W3033460778 cites W2022556757 @default.
• W3033460778 cites W2022863677 @default.
• W3033460778 cites W2023464945 @default.
• W3033460778 cites W2031528956 @default.
• W3033460778 cites W2031552413 @default.
• W3033460778 cites W2032624987 @default.
• W3033460778 cites W2039308959 @default.
• W3033460778 cites W2043808171 @default.
• W3033460778 cites W2047543420 @default.
• W3033460778 cites W2051884986 @default.
• W3033460778 cites W2053072887 @default.
• W3033460778 cites W2059767978 @default.
• W3033460778 cites W2060967263 @default.
• W3033460778 cites W2063189599 @default.
• W3033460778 cites W2064719335 @default.
• W3033460778 cites W2073668218 @default.
• W3033460778 cites W2079700516 @default.
• W3033460778 cites W2082401947 @default.
• W3033460778 cites W2083318583 @default.
• W3033460778 cites W2096661435 @default.
• W3033460778 cites W2100835521 @default.
• W3033460778 cites W2101335477 @default.
• W3033460778 cites W2104227526 @default.
• W3033460778 cites W2109460887 @default.
• W3033460778 cites W2110484821 @default.
• W3033460778 cites W2114276024 @default.
• W3033460778 cites W2117306498 @default.
• W3033460778 cites W2125305773 @default.
• W3033460778 cites W2125763669 @default.
• W3033460778 cites W2127819105 @default.
• W3033460778 cites W2131843183 @default.
• W3033460778 cites W2134572790 @default.
• W3033460778 cites W2135806696 @default.
• W3033460778 cites W2139226057 @default.
• W3033460778 cites W2140336044 @default.
• W3033460778 cites W2143061557 @default.
• W3033460778 cites W2143486619 @default.
• W3033460778 cites W2145383858 @default.
• W3033460778 cites W2153514014 @default.
• W3033460778 cites W2153653527 @default.
• W3033460778 cites W2156149445 @default.
• W3033460778 cites W2156339098 @default.
• W3033460778 cites W2156850322 @default.
• W3033460778 cites W2158529492 @default.
• W3033460778 cites W2159032431 @default.
• W3033460778 cites W2159739693 @default.
• W3033460778 cites W2162640763 @default.
• W3033460778 cites W2164678034 @default.
• W3033460778 cites W2165326718 @default.
• W3033460778 cites W2171293769 @default.
• W3033460778 cites W2171651771 @default.
• W3033460778 cites W2171737529 @default.
• W3033460778 cites W2190376675 @default.
• W3033460778 cites W2258150272 @default.
• W3033460778 cites W2290862726 @default.

• next